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Drusen are tiny yellow or white fat globules and extracellular material that build up in the retina of the eye or on the optic nerve head. It is a common early sign of age-related macular degeneration (ARMD). For other uses, see Fat (disambiguation). ... Human eye cross-sectional view. ... gonfly]].]] In most vertebrates and some mollusks, the eye works by allowing light to enter it and project onto a light-sensitive panel of cells known as the retina at the rear of the eye, where the light is detected and converted into electrical signals, which are then transmitted to... The optic nerve is the nerve that transmits visual information from the retina to the brain. ... Listen to this article · (info) This audio file was created from an article revision dated 2005-07-19, and does not reflect subsequent edits to the article. ...
Drusen occurs as hard drusen (small, solid deposits that seem harmless) or larger deposits of soft drusen with indistinct borders. Soft drusen accumulating between the retinal pigment epithelium (RPE) and Bruch's membrane force these two structures apart. The pigmented layer of the retina consists of a single stratum of cells. ... Bruchs membrane is the innermost layer of the choroid. ...
Most people over 40 have a small amount of hard drusen that can join to form soft drusen in ARMD. However, not all soft drusen comes from hard drusen.
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