Dukes of Medina Sidonia (1445)

• Juan Alfonso de Guzman El Bueno, 1st Duke of Medina Sidonia (1410-1468)
• Enrique de Guzman El Bueno, 2nd Duke of Medina Sidonia (d. 1492)
• Juan Alfonso Perez de Guzman El Bueno, 3rd Duke of Medina Sidonia (1464-1507)
• Enrique de Guzman El Bueno, 4th Duke of Medina Sidonia (d. 1512)
• Alfonso Perez de Guzman El Bueno, 5th Duke of Medina Sidonia (d. 1549)
• Juan Alfonso Perez de Guzman El Bueno, 6th Duke of Medina Sidonia (d. 1559)
• Alonso de Guzman El Bueno, 7th Duke of Medina Sidonia (1549-1615) Admiral of the Armada
• Juan Manuel de Guzman El Bueno, 8th Duke of Medina Sidonia (1579-1636)
• Gaspare Alfonso de Guzman El Bueno, 9th Duke of Medina Sidonia (d. 1664)
• Gaspar Juan Perez de Guzman El Bueno, 10th Duke of Medina Sidonia (d. 1667)
• Juan Claros de Guzman El Bueno, 11th Duke of Medina Sidonia (1642-1713)
• Manuel de Guzman El Bueno, 12th Duke of Medina Sidonia (1671-1721)
• Domingo José Carlos de Guzman El Bueno, 13th Duke of Medina Sidonia (d. 1739)
• Pedro de Alcantara Alonso Perez de Guzman El Bueno, 14th Duke of Medina Sidonia (1724-1779)
• José Alvarez de Toledo, 15th Duke of Medina Sidonia (d. 1796)
• Francisco de Borja Alvarez de Toledo, 16th Duke of Medina Sidonia (1763-1821)
• Pedro de Alcantara Alvarez de Toledo Palafox, 17th Duke of Medina Sidonia (1803-1867)
• Joaquin Alvarez de Toledo, 18th Duke of Medina Sidonia (1865-1915)
• Joaquin Alvarez de Toledo, 19th Duke of Medina Sidonia (1894-1955)
• Luisa Isabel Alvarez de Toledo, 20th Duchess of Medina Sidonia (b. 1936)