NationMaster - Encyclopedia: Dupuytren's contracture

Dupuytren's contracture (also known as Morbus Dupuytren) is a fixed flexion contracture of the hand where the fingers bend towards the palm and cannot be fully extended (straightened). It is named after the famous surgeon Baron Guillaume Dupuytren, who described an operation to correct the affliction. Image File history File links Metadata Size of this preview: 800 Ã— 600 pixelsFull resolution (2560 Ã— 1920 pixel, file size: 1. ... The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) is a coding of diseases and signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or diseases, as classified by the World Health Organization (WHO). ... // M00-M99 - Diseases of the musculoskeletal system and connective tissue (M00-M25) Arthropathies (M00-M03) Infectious arthropathies (M00) Pyogenic arthritis (M01) Direct infections of joint in infectious and parasitic diseases classified elsewhere (M02) Reactive arthropathies (M023) Reiters disease (M03) Postinfective and reactive arthropathies in diseases classified elsewhere (M05-M14... The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ... The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and - when possible - links them to the relevant genes in the human genome. ... The Disease Bold textDatabase is a free website that provides information about the relationships between medical conditions, symptoms, and medications. ... MedlinePlus (medlineplus. ... eMedicine is an online clinical medical knowledge base that was founded in 1996. ... In anatomy, Flexion is movement whereby bones or other objects are brought closer together. ... Contracture can refer to: Dupuytrens contracture Volkmanns contracture Capsular contracture This is a disambiguation page: a list of articles associated with the same title. ... For other uses, see Hand (disambiguation). ... This article does not cite any references or sources. ... â€œSurgeonâ€ redirects here. ... Guillaume Dupuytren, Baron (October 6, 1777 - February 8, 1835) was a French anatomist and military surgeon. ... â€œSurgeonâ€ redirects here. ...

The ring finger and little finger are the fingers most commonly affected; the middle finger may be affected in advanced cases, but index finger and thumb are nearly always spared. Dupuytren's contracture progresses slowly and is usually painless. In patients with this condition, the tissues under the skin on the palm of the hand thicken and shorten so that the tendons connected to the fingers cannot move freely. The palmar aponeurosis becomes hyperplastic and undergoes contracture. As a result, the affected fingers start to bend more and more and cannot be straightened. The ring finger is the fourth digit of the human hand, and the second most ulnar finger, located between the middle finger and the little finger. ... The little finger, often called the pinky in American English and pinkie in Scottish English (from the Dutch word pink, meaning little finger), is the most ulnar and usually smallest finger of the human hand, opposite the thumb, next to the ring finger. ... This article is about the vulgar gesture. ... The Index finger The index finger, pointer finger or forefinger is the second digit of a human hand, located between the thumb and the middle finger. ... For other uses, see Thumb (disambiguation). ... Pain redirects here. ... Biological tissue is a collection of interconnected cells that perform a similar function within an organism. ... Beyond overall skin structure, refer below to: See-also. ... A tendon (or sinew) is a tough band of fibrous connective tissue that connects muscle to bone and is built to withstand tension. ... The palmar aponeurosis (palmar fascia) invests the muscles of the palm, and consists of central, lateral, and medial portions. ...

Incidence increases after the age of 40; at this age men are affected more often than women. After the age of 80 the distribution is about even. In optics one considers angles of incidence. ... In biology, senescence is the combination of processes of deterioration which follow the period of development of an organism. ... This article concerns how a man differs from women. ... Image of a woman on the Pioneer plaque sent to outer space. ...

Symptoms

In Dupuytren's disease, the tough connective tissue within one's hand becomes abnormally thick, which can cause the fingers to curl, and can result in impaired function of the fingers, especially the small and ring fingers. It usually has a gradual onset, often beginning as a tender lump in the palm. Over time, pain associated with the condition tends to go away, but tough bands of tissue may develop. [1] These bands, which are the source of the reduced mobility commonly associated with the condition, are visible on the surface of the palm, and may appear similar to a small callus. It commonly develops in both hands, and has no connection to dominant- or non-dominant hands, nor any correlation with right- or left-handedness. This article does not cite any references or sources. ... This article is about calluses and corns of human skin. ...

The contracture sets on very slowly, especially in women. However, when present in both hands, and when there is associated foot involvement, it tends to accelerate more rapidly.

Risk factors and possible causes

Regular operation of heavy machinery increases one's risk of developing Dupuytren's contracture; family history, diabetes, liver disease, alcoholism, epilepsy and pulmonary tuberculosis are also factors. Surgery of the hand may trigger growth of Dupuytren nodules and cords if an inclination existed before. Dupuytren's contracture may accompany fibrosing syndromes such as Peyronie's disease, Ledderhose's disease and Riedel's thyroiditis. In medicine, a family history consists of information about disorders that a patients direct blood relatives have suffered from. ... This article is about the disease that features high blood sugar. ... The liver is an organ in vertebrates including humans. ... Alcoholism is the consumption of, or preoccupation with, alcoholic beverages to the extent that this behavior interferes with the drinkers normal personal, family, social, or work life, and may lead to physical or mental harm. ... The heart and lungs (from an older edition of Grays Anatomy) The lung is an organ belonging to the respiratory system and interfacing to the circulatory system of air-breathing vertebrates. ... Tuberculosis (abbreviated as TB for tubercle bacillus or Tuberculosis) is a common and deadly infectious disease caused by mycobacteria, mainly Mycobacterium tuberculosis. ... In medicine, the term syndrome is the association of several clinically recognizable features, signs, symptoms, phenomena or characteristics which often occur together, so that the presence of one feature alerts the physician to the presence of the others. ... Peyronies disease is a connective tissue disorder involving the growth of fibrous plaques in the soft tissue of the penis affecting as many as 1-4% of men. ... Ledderhoses Disease, also known as Morbus Ledderhose, plantar fibromatosis, and plantar aponeurosis, is a non-malignant thickening of the feets deep connective tissue, or fascia. ... Riedels thyroiditis, also called Riedels struma is a chronic form of thyroiditis. ...

Those of northern European descent are markedly at risk. Samuel Beckett, Ronald Reagan, Margaret Thatcher, and Bill Nighy are among the most famous patients. Interestingly, although this a predominantly caucasian disease, many Caribbean blacks can present with contractures, and all can trace a distant relative to Britain or Ireland.^{[citation needed]} Samuel Barclay Beckett (13 April 1906 â€“ 22 December 1989) was an Irish dramatist, novelist and poet. ... Reagan redirects here. ... Margaret Hilda Thatcher, Baroness Thatcher, LG, OM, PC, FRS (nÃ©e Roberts; born 13 October 1925) served as British Prime Minister from 1979 to 1990 and leader of the Conservative Party from 1975 until 1990, being the first and to date only woman to hold either post. ... Bill Nighy (IPA: ; born December 12, 1949) is a Golden Globe and BAFTA-award winning English actor. ...

Correlations have also been found between Dupuytren's contracture and: For other uses, see Scandinavia (disambiguation). ... Northern Europe Northern Europe is the northern part of the European continent. ... For other uses, see Viking (disambiguation). ...

There is also some speculation that Dupuytren's may be caused by physical trauma, such as manual labor or other over-exertion of the hands. However, the fact that Dupuytren's is not connected with handedness casts some doubt on this claim. [5]. For an overview on research literature see also Dupuytren's work related?. This article is about the disease that features high blood sugar. ... Alcoholism is the consumption of, or preoccupation with, alcoholic beverages to the extent that this behavior interferes with the drinkers normal personal, family, social, or work life, and may lead to physical or mental harm. ... The liver is an organ in vertebrates including humans. ...

Treatment

Surgical management consists of opening the skin over the affected cords and excising, removing, the fibrous tissue. The fingers may then be brought out to length with the help of postoperative therapy. The procedure is not curative in that remaining non-affected fascia may still develop Dupuytren's disease later on, and therefore the patients may need repeat surgery. In addition, the thickened fascia often invests the digital nerves and arteries, so there is some risk of nerve and/or arterial injury. Triamcinolone (trade names Kenalog, Aristocort, Nasacort, Tri-Nasal, Triderm, Azmacort, Trilone, Volon A, Tristoject, Fougera;) is a synthetic corticosteroid given orally, by injection, inhalation, or as a topical ointment or cream. ...

Treatment of Dupuytren's disease with low energy x-rays (radiotherapy) may cure Morbus Dupuytren on a long term, specifically if applied in early stages of the disease. Needle aponevrotomy is a minimal invasive technique where the cords are weakened through the insertion and manipulation of a small needle. Once weakened, the offending cords may be snapped by simply pulling the finger(s) straight. The nodules are not removed and might start growing again. Currently in phase III of Food and Drug Administration (FDA) approval is another promising therapy, the injection of collagenase. This procedure is similar to needle aponevrotomy, however the chords are weakened through the injection of small amounts of an enzyme that dissolves them. In medicine, a clinical trial (synonyms: clinical studies, research protocols, medical research) is a research study. ... â€œFDAâ€ redirects here. ... Collagenases are enzymes that break the peptide bonds in collagen. ...

Dupuytren's contracture is not a dangerous condition, and often no treatment is necessary. Even when treatment is used, there is no permanent way to stop or cure the infliction. If there is a painful lump present, an injection can often help alleviate the pain. If pain persists or the function of the hand becomes seriously impaired, individuals often choose to have surgery. This surgery usually entails removing or separating the thickened bands, and is unlikely to cause any major complications or side effects, although in serious cases, some minor skin grafting may be necessary. Any damaged skin or tissue in the surgically affected area of the hand will heal fairly quickly, and reducing bloodflow during the healing period helps reduce pain. This may be done by keeping the hand raised or elevated so that blood does not pool in the affected area.

After surgical treatment, the condition may worsen in inadequately excised diseased tissue or re-develop in previously normal tissue.

External links

Categories: All articles with unsourced statements | Articles with unsourced statements since March 2007 | Diseases involving the fasciae | Rare diseases The human musculoskeletal system is the musculoskeletal system that gives us the ability to move. ... Connective tissue is one of the four types of tissue in traditional classifications (the others being epithelial, muscle, and nervous tissue. ... An Arthropathy is a disease of a joint. ... Arthritis (from Greek arthro-, joint + -itis, inflammation; plural: arthritides) is a group of conditions where there is damage caused to the joints of the body. ... This article does not adequately cite its references or sources. ... Rheumatoid arthritis (RA) is traditionally considered a chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints. ... Psoriatic arthritis (or Arthropathic psoriasis) is a type of inflammatory arthritis that affects around 20% of people suffering from the chronic skin condition Psoriasis. ... Definition Rheumatoid Arthritis (chronic) & Splenomegaly, â†“ WCC, +++ RhF Complications Recurrent Infection, Hypersplenism â†’ causing 2Â° anaemia Â± thrombocytopenia) Lymphadenopathy Skin hyperpigmentation & cutaneous ulceration Treatment That of RA + Splenectomy may improve neutropenia] ... This article does not deal with the more general topic of childhood arthritis. ... Stills disease is a form of juvenile idiopathic arthritis, characterized by high spiking fevers and transient rashes, named after the English physician Sir George Frederic Still (1861-1941). ... Categories: Stub ... Osteoarthritis / Osteoarthrosis (OA, also known as degenerative arthritis, degenerative joint disease, arthrosis or in more colloquial terms wear and tear), is a condition in which low-grade inflammation results in pain in the joints, caused by wearing of the cartilage that covers and acts as a cushion inside joints. ... Heberdens nodes are seen in the distal interphalangeal joints. ... Bouchards nodes are seen in the proximal interphalangeal joints. ... The introduction to this article provides insufficient context for those unfamiliar with the subject matter. ... A bunion (hallux valgus) is a sometimes painful structural deformity of the bones and the joint between the foot and big toe. ... Hallux rigidus is a condition restricting dorsiflexion of the hallux (big toe). Duke Orthopedics hallux_rigidus_and_cheilectomy -66715641 at GPnotebook Overview at aaos. ... Hallux varus is a deformity of the great toe joint where the Hallux (or Great Toe) is deviated medially (towards the midline of the body) away from the 1st metatarsal. ... A Hammer toe deformity is a condition of the toe where the toe is bent downward. ... In orthopedics, a valgus deformity is a term for the outward angulation of the distal segment of a bone or joint. ... In orthopedics, a varus deformity is a term for the inward angulation of the distal segment of a bone or joint. ... Wrist drop is a condition where a person can not extend their wrist and it hangs flaccidly. ... Foot drop is a deficit in turning the ankle and toes upward (dorsiflexion). ... Flat feet, also called pes planus or fallen arches, is a condition in which the arch of the foot collapses, with the entire sole of the foot coming into complete or near-complete contact with the ground. ... Club foot. ... Unequal leg length or leg length inequality (LLI) refers to a medical condition where the legs are of different sizes. ... Winged scapula is a condition in which the medial border (the side nearest the spine) of a persons scapula is abnormally positioned laterally and posteriorly (outward and backward). ... Chondromalacia Patellae (also known as CMP, Patello-Femoral Pain Syndrome, or Runners Knee) is a discomfort or dull pain in the knee or just under or around the knee. ... Connective tissue is one of the four types of tissue in traditional classifications (the others being epithelial, muscle, and nervous tissue. ... Polyarteritis nodosa (or periarteritis nodosa) is a serious blood vessel disease. ... Churg-Strauss syndrome is a necrotizing vasculitis characterized by eosinophilia. ... Kawasaki disease, also known as lymph node syndrome, mucocutaneous node disease, infantile polyarteritis and Kawasaki syndrome, is a poorly understood self-limited vasculitis that affects many organs, including the skin and mucous membranes, lymph nodes, blood vessel walls, and the heart. ... Hypersensitivity vasculitis (or hypersensitivity angiitis or leukocytoclastic vasculitis) is usually due to a hypersensitivity reaction to a known drug, auto-antigens or infectious agents such as bacteria. ... Goodpastureâ€™s syndrome (also known as Goodpastureâ€™s disease and anti-glomerular basement membrane disease or anti-GBM disease) was first described by Ernest Goodpasture in 1919. ... In medicine (rheumatology), Wegeners granulomatosis is a form of vasculitis that affects the lungs, kidneys and other organs. ... Arteritis is inflammation of the walls of arteries, usually as a result of infection or auto-immune response. ... Takayasus arteritis is an inflammatory disease of unknown etiology that affects the aorta and its branches. ... Temporal arteritis, also called giant cell arteritis (GCA) is an inflammatory disease of blood vessels (most commonly large and medium arteries of the head). ... Microscopic polyangiitis (MPA) is an ill-defined autoimmune disease characterized by pauci-immune, necrotizing, small-vessel vasculitis without clinical or pathological evidence of necrotizing granulomatous inflammation. ... Drug-induced lupus erythematosus (DIL or DILE) is an autoimmune disorder, similar to systemic lupus erythematosus (SLE), which is induced by chronic use of certain drugs. ... X-Ray of the knee in a patient with dermatomyositis. ... Juvenile dermatomyositis (JDM) is an autoimmune disease that manifests itself in children. ... {{ }} Polymyositis is a type of inflammatory myopathy, related to dermatomyositis and inclusion body myositis. ... Scleroderma is a rare, chronic disease characterized by excessive deposits of collagen in the skin or other organs. ... SjÃ¶grens syndrome is an autoimmune disorder in which immune cells attack and destroy the glands that produce tears and saliva. ... BehÃ§et disease (BehÃ§ets syndrome, Morbus BehÃ§et, silk road disease) is a chronic condition due to disturbances in the bodyâ€™s immune system. ... Polymyalgia Rheumatica (PMR) - is a disorder associated with pain in the shoulder and hip. ... Eosinophilic fasciitis (pronounced ), or EF, is a form of fasciitis. ... Hypermobility (also called double-jointedness, hypermobility syndrome or hyperlaxity) describes joints that stretch farther than is normal. ... Dorsopathy is a term used to describe various diseases (-pathy) of the back and or spine (dorso-). Although the terms dorsalgia and dorsopathy are sometimes used interchangeably, they do not mean quite the same thing. ... Kyphosis (Greek - kyphos, a hump), in general terms, is a curvature of the upper spine. ... Lordosis is a term used to describe the direction of the curvature of the five lumbar and seven cervical vertebrae of the vertebral column. ... The medical term kyphosis has several meanings. ... Spondylolysis is a defect in the pars interarticularis of a vertebra. ... Torticollis, or wry neck, is a condition in which the head is tilted toward one side, and the chin is elevated and turned toward the opposite side. ... Not to be confused with spondylosis or spondylolysis. ... In medicine, Spondylopathies is a general term for disorders of the vertebrae. ... This article does not cite any references or sources. ... Schmorls Nodes are considered to be vertical disc herniations through the cartilaginous vertebral body endplates, resulting in compression fractures. ... Degeneration of the intervertebral disc, which is often called degenerative disc disease (DDD) of the spine, is a common disorder of the lower spine. ... Coccydynia is a medical condition characterized by pain in the coccyx or tailbone area. ... Back pain (also known dorsalgia) is pain felt in the back that may originate from the muscles, nerves, bones, joints or other structures in the spine. ... Radiculopathy is not a specific condition, but rather a description of a problem in which one or more nerves are affected and do not work properly. ... Sciatica is pain caused by general compression and/or irritation of one of five nerve roots that are branches of the sciatic nerve. ... Lumbago is a term used to refer to low back pain. ... It has been suggested that this article or section be merged with Back pain. ... In medicine, the term soft tissue refers to tissues that connect, support, or surround other structures and organs of the body. ... Myositis ossificans comprises two syndromes characterized by heterotopic calcification of muscle. ... Fibrodysplasia ossificans progressiva (FOP), is a rare disease of the connective tissue. ... Synovitis is the medical term for inflammation of a synovial membrane, which line those joints which possess cavities. ... Tenosynovitis is the inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon. ... Stenosing tenosynovitis is the progressive restriction of the sheath surrounding a tendon, causing inflammation (tenosynovitis). ... Trigger finger, or trigger thumb, is a type of stenosing tenosynovitis in which the sheath around a tendon in a thumb or finger becomes swollen or a nodule forms on the tendon itself. ... DeQuervains syndrome (also known as washerwomans sprain, Radial styloid tenosynovitis, De Quervains disease or mothers wrist), named for Swiss surgeon Fritz de Quervain who first identified it in 1885, is an inflammation of the sheath or tunnel that surrounds two tendons that control movement of the... Bursitis is the inflammation of one or more bursae, or small sacs of synovial fluid, in the body. ... Olecranon bursitis is a clinical condition characterised by pain, swelling and inflammation of the olecranon bursa. ... This article or section does not cite its references or sources. ... Trochanteric bursitis is inflammation of the trochanteric bursa. ... Plantar fasciitis is a painful inflammatory condition caused by excessive wear to the plantar fascia of the foot. ... There are very few or no other articles that link to this one. ... Necrotizing fasciitis or fasciitis necroticans, commonly known as flesh-eating bacteria, is a rare infection of the deeper layers of skin and subcutaneous tissues, easily spreading across the fascial plane within the subcutaneous tissue. ... In medicine, fasciitis refers to an inflammation of the fascia. ... Categories: Move to Wiktionary | Medicine stubs ... In medicine, an enthesopathy refers to an inflammation of entheses. ... Iliotibial Band Syndrome (ITBS or ITBFS, for Iliotibial Band Friction Syndrome) is a common thigh injury generally associated with running. ... Achilles tendinitis is inflammation of the Achilles tendon. ... Golfers elbow, or medial epicondylitis, is an inflammatory condition of the elbow which in some ways is similar to tennis elbow. ... Tennis elbow is a condition where the outer part of the elbow becomes painful and tender, usually as a result of a specific strain or overuse. ... Metatarsalgia is a general term used to refer to any painful foot condition affecting the metatarsal region of the foot. ... Bone spurs, also known as osteophytes, are bony projections that form along joints. ... Tendonitis (also tenonitis or tendinitis) is an inflammation of a tendon. ... Myalgia means muscle pain and is a symptom of many diseases and disorders. ... Bone disease refers to the medical conditions which affect the bone. ... Osteoporosis is a disease of bone in which the bone mineral density (BMD) is reduced, bone microarchitecture is disrupted, and the amount and variety of non-collagenous proteins in bone is altered. ... Pseudarthrosis is the movement of a bone at the location of a fracture resulting from inadequate healing of the fracture. ... This article is about stress wienerfractures in bones. ... Monostotic fibrous dysplasia (or monostotic osteitis fibrosa) is a form of fibrous dysplasia where only one bone is involved. ... Skeletal fluorosis is a bone disease exclusively caused by excessive consumption of fluoride. ... An aneurysmal bone cyst is an expansile osteolytic lesion with a thin wall, containing blood-filled cystic cavities. ... Osteomyelitis is an infection of bone, usually caused by pyogenic bacteria or mycobacteria. ... Avascular necrosis is a disease resulting from the temporary or permanent loss of the blood supply to the bones. ... Bold text X-ray of Pagets disease Pagets disease, otherwise known as osteitis deformans, is a chronic disorder that typically results in enlarged and deformed bones. ... Complex Regional Pain Syndrome (CRPS) is a chronic progressive disease characterized by severe pain, swelling and changes in the skin. ... Dissolution or degeneration of bone tissue through disease. ... In medicine, Chondropathy refers to a disease of the cartilage. ... Osteochondrosis is a orthopedic disease. ... Legg-CalvÃ©-Perthes syndrome is a degenerative disease of the hip joint, where a loss of bone mass leads to some degree of collapse of the hip joint, that is, to deformity of the ball of the femur and the surface of the hip socket. ... Osgood-Schlatter disease (also known as tibial tubercle traumatic apophysitis) is an inflammation of the growth plate at the tibial tuberosity. ... KÃ¶hler disease (also spelled Kohler) is a rare bone disorder of the foot found in children between six and nine years of age. ... Severs disease, or calcaneal apophysitis, is the most frequent cause of heel pain in children between the ages of 8 and 13 and is due to an inflammation of growing plates, the calcaneus in the back of the foot due to the rapid growth of bone when compared to... Osteochondritis Dessicans is when a loose piece of bone and cartilage seperates from the end of the bone because of a loss of blood supply and insuffecient amounts of calcium. ... Tietzes syndrome, also known as costochondritis, is a benign inflammation of one or more of the costal cartilages. ... // Q00-Q99 - Congenital malformations, deformations and chromosomal abnormalities (Q00-Q07) Congenital malformations of the nervous system (Q00) Anencephaly and similar malformations (Q01) Encephalocele (Q02) Microcephaly (Q03) Congenital hydrocephalus (Q04) Other congenital malformations of brain (Q05) Spina bifida (Q06) Other congenital malformations of spinal cord (Q07) Other congenital malformations of nervous...

Contents

Symptoms GA_googleFillSlot("encyclopedia_square");

Risk factors and possible causes

Treatment

External links

Symptoms