Look up dysphoria in Wiktionary, the free dictionary.
Dysphoria is the opposite of euphoria. It is generally characterized as a feeling of emotional and/or mental discomfort, restlessness, malaise, and depression. A person suffering from dysphoria will feel that "Things aren't the way they are supposed to be." One type of dysphoria is gender dysphoria; people who suffer from this disorder feel uncomfortable with their identity in the gender/sex they have been assigned. Chronic dysphoric mood states may also be a contributing factor in the development of eating disorders and depression. Wikipedia does not have an article with this exact name. ... Wiktionary is a Wikimedia Foundation project intended to be a free wiki dictionary (hence: Wiktionary) (including thesaurus and lexicon) in every language. ... Look up euphoria in Wiktionary, the free dictionary. ... Malaise is a term used to refer to a general state of discomfort, tiredness, or illness. ... Sadness redirects here. ... Gender identity disorder as identified by psychologists and medical doctors is a condition where a person who has been assigned one gender (usually at birth on the basis of their sex, but compare intersexual) but identifies as belonging to another gender, or does not conform with the gender role their... Look up depression in Wiktionary, the free dictionary. ...
Dysphoria can be differentiated from depression in that it tends to be an agitated feeling. That is, dysphoria is often described by sufferers as a "bad high" as opposed to the "low" of depression. Sufferers of bipolar disorder often suffer from dysphoric highs, making the stereotype of "bad when low, great when up" bitterly ironic. Bipolar disorder (previously known as manic depression) is a diagnostic category describing a class of mood disorders where the person experiences states or episodes of depression and/or mania, hypomania, and/or mixed states. ...
Dysphoria can be induced by opioids acting on Kappa receptors in the central nervous system.
Dysphoria persisting over time, may lead to adverse clinical consequences such as treatment non-adherence, substance abuse, poor clinical outcome, increased suicidality and compromised quality of life.
Interference with the physiological processes of hedonic capacity by the neuroleptics due to their dopaminergic blocking action in the prefrontal cortex and the shell of nucleus accumbens is the putative mediating mechanism underlying the occurrence of dysphoric responses.
CONCLUSION: Viewing neuroleptic dysphoria within a broader spectrum of disorders of subjective tolerability and exploring its neurobiological mechanisms is relevant to addressing the nuances of antipsychotic therapy, and could help unravel the questions surrounding the pathophysiology of depression, substance abuse and other dysphoric clinical states.
Dysphoria (from Greek δύσφορος (dysphoros), from δυσ-, difficult, and φέρω, to bear) is generally characterized as an unpleasant or uncomfortable mood, such as sadness (depressed mood), anxiety, irritability, or restlessness.
Dysphoria is usually experienced during depressive episodes, but in people with bipolar disorder, it may also be experienced during manic or hypomanic episodes.
Dysphoria in the context of a mood disorder indicates a heightened risk of suicide.
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