EGTA (chemical)
IUPAC name	glycol-bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid
Identifiers
CAS number	[67-42-5]
Properties
Molecular formula	C14H24N2O10
Molar mass	380.35 g/mol
Melting point	241 °C, 514 K, 466 °F IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... Molar mass is the mass of one mole of a chemical element or chemical compound. ... The melting point of a crystalline solid is the temperature at which it changes state from solid to liquid. ...
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

EGTA is the chemical compound ethylene glycol tetraacetic acid, a chelating agent that is related to the better known EDTA, but with a much higher affinity for calcium than for magnesium ions. It is useful for making buffer solutions that resemble the environment inside living cells, where calcium ions are usually at least a thousandfold less concentrated than magnesium. In chemistry, the standard state of a material is its state at 1 bar (100 kilopascals) and 25 degrees Celsius (298. ... A chemical compound is a chemical substance consisting of two or more different chemically bonded chemical elements, with a fixed ratio determining the composition. ... Chelation (from Greek, claw like) describes the reversible binding of an organic ligand, the chelator or chelating agent, to a metal ion, forming a metal complex, the chelate. ... EDTA is a popular acronym for the chemical compound ethylenediaminetetraacetic acid. ... General Name, Symbol, Number calcium, Ca, 20 Chemical series alkaline earth metals Group, Period, Block 2, 4, s Appearance silvery white Atomic mass 40. ... General Name, Symbol, Number magnesium, Mg, 12 Chemical series alkaline earth metals Group, Period, Block 2, 3, s Appearance silvery white Atomic mass 24. ... “Multivalent” redirects here. ... Acids and bases: Acid-base reaction theories pH Self-ionization of water Buffer solutions Systematic naming Electrochemistry Acid-base extraction Acids: Strong acids Weak acids Superacids Lewis acids Mineral acids Organic acids Bases: Strong bases Weak bases Superbases Lewis bases Organic bases edit Buffer solutions are solutions which resist change... Drawing of the structure of cork as it appeared under the microscope to Robert Hooke from Micrographia which is the origin of the word cell. Cells in culture, stained for keratin (red) and DNA (green). ...

The pKa for binding of calcium ions by tetrabasic EGTA is 11.00, but the protonated forms do not significantly contribute to binding, so at pH 7, the apparent pKa becomes 6.91.

EGTA has also been used experimentally for the treatment of animals with cerium poisoning and for the separation of thorium from monazite. EGTA is used as a compound in elution buffer in the protein purification technique known as Tandom Affinity Purification (TAP), in which recombinant fusion proteins are bound to Calmodulin beads & eluted out by adding EGTA. General Name, Symbol, Number cerium, Ce, 58 Chemical series lanthanides Group, Period, Block n/a, 6, f Appearance silvery white Atomic mass 140. ... Separation may refer to a several different subjects: In chemistry, separation refers to the separation process. ... General Name, Symbol, Number thorium, Th, 90 Chemical series Actinides Group, Period, Block n/a, 7, f Appearance silvery white Atomic mass 232. ... Monazite powder In geology, the mineral monazite is a reddish-brown phosphate containing rare earth metals and an important source of thorium, lanthanum, and cerium. ...

See also

• EDTA
• BAPTA

EDTA is a popular acronym for the chemical compound ethylenediaminetetraacetic acid. ... Categories: Stub | Amines | Aromatic compounds | Carboxylic acids | Ethers ...

External links

• Links to external chemical sources