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Encyclopedia > EM Data Bank

The EM Data Bank or EMDB is an extension of the Protein Data Bank (PDB) for 3D data collected from Cryo-Electron Microscopy data. This site is only site that provides the three-dimensional for non-viruses (which is filled by the Viper EMDB at Scripps). The Protein Data Bank (PDB) is a repository for 3-D structural data of proteins and nucleic acids. ... Cryo-electron microscopy (sometimes called cryoEM or electron cryomicroscopy) is a form of electron microscopy (EM) where the sample is studied at cryogenic temperatures (generally liquid nitrogen temperatures). ... TSRIs Beckman Center for Chemical Sciences The Scripps Research Institute (TSRI) is a medical research facility that focuses on research in the basic biomedical sciences. ...


While still in its early days, Cryo-Electron Microscopy is becoming an important tool in understanding biological molecules and all of these molecules are deposited in the EMDB. The PDB no longer accepts low-resolution structures. Cryo-electron microscopy (sometimes called cryoEM or electron cryomicroscopy) is a form of electron microscopy (EM) where the sample is studied at cryogenic temperatures (generally liquid nitrogen temperatures). ...


References

  • M. Tagari, et al. (2002). "New electron microscopy database and deposition system”. Trends Biochem Sci, 27 (11): p. 589. PMID 12417136
  • S. D. Fuller (2003). “Depositing electron microscopy maps”. Structure, 11 (1): pp. 11–12. PMID 12517335
  • K. Henrick, R. Newman, M. Tagari, and M. Chagoyen (2003). “EMDep: a web-based system for the deposition and validation of high-resolution electron microscopy macromolecular structural information”. J Struct Biol, 144 (1-2): pp. 228–237. PMID 14643225
  • J. B. Heymann, M. Chagoyen, and D. M. Belnap (2005). “Common conventions for interchange and archiving of three-dimensional electron microscopy information in structural biology”. J Struct Biol, 151 (2): pp. 196–207. PMID 16043364
  • M. Tagari, et al. (2006). “E-MSD: improving data deposition and structure quality”. Nucleic Acids Res, 34 (Database issue): pp. 287–290. PMID 16381867

See also

There are a large number of software tools or software applications that have been specifically developed for the field sometimes referred to as molecular microscopy or cryo-electron microscopy or cryoEM. Several special issues of the Journal of Structural Biology (see references below) have been specifically devoted to descriptions of... Cryo-electron microscopy (sometimes called cryoEM or electron cryomicroscopy) is a form of electron microscopy (EM) where the sample is studied at cryogenic temperatures (generally liquid nitrogen temperatures). ...

External links

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