The Marquess holds the subsidiary titles of Earl of Hillsborough (Peerage of Great Britain, 1772), Earl of Hillsborough (Peerage of Ireland, 1751), Viscount Fairford (Peerage of Great Britain, 1772), Viscount Hillsborough (Peerage of Ireland, 1717), Viscount Kilwarlin (Peerage of Ireland, 1751), Baron Harwich (Peerage of Great Britain, 1756), and Baron Hill of Kilwarlin (Peerage of Ireland, 1717).
He was usually called the Earl of Hillsborough in America when he served as Secretary of State for the Colonies in 1768–1772, a critical period leading toward the American Revolution.
In 1751 he was created Earl of Hillsborough in the Irish peerage; in 1754 he was made Comptroller of the Royal Household and an English privy counsellor; and in 1756 he became a peer of Great Britain as Baron Harwich.
From 1768 to 1772 Hillsborough was Secretary of State for the Colonies and also president of the board of trade, becoming an English earl on his retirement; in 1779 he was made Secretary of State for the Southern Department, and he was created Marquess of Downshire seven years after his final retirement in 1782.