The title of Earl of Macclesfield has been created twice, first in the Peerage of England in 1679 (extinct 1702) and then in the Peerage of Great Britain in 1721.

The first Earls of Macclesfield, from the Gerard family, held the subsidiary titles of Viscount Brandon (1679) and Baron Gerard of Brandon (1645), both in the Peerage of England.

The present Earls, from the Parker family, possess the subsidiary titles of Viscount Parker (1721) and Baron Parker of Macclesfield (1716), both in the Peerage of Great Britain.

Earls of Macclesfield, First Creation (1679)

• Charles Gerard, 1st Earl of Macclesfield (1618-1694)
• Charles Gerard, 2nd Earl of Macclesfield (1659-1701)
• Fitton Gerard, 3rd Earl of Macclesfield (1665-1702)

Earls of Macclesfield, Second Creation (1721)

• Thomas Parker, 1st Earl of Macclesfield (1667-1732)
• George Parker, 2nd Earl of Macclesfield (c. 1697-1764)
• Thomas Parker, 3rd Earl of Macclesfield (1723-1795)
• George Parker, 4th Earl of Macclesfield (1755-1842)
• Thomas Parker, 5th Earl of Macclesfield (1763-1850)
• Thomas Augustus Wolstenholme Parker, 6th Earl of Macclesfield (1811-1896)
• George Loveden William Henry Parker, 7th Earl of Macclesfield (1888-1975)
• George Roger Alexander Thomas Parker, 8th Earl of Macclesfield (1914-1992)
• Richard Timothy George Mansfield Parker, 9th Earl of Macclesfield (b. 1943)