Anterior lens luxation

Ectopia lentis is a displacement or malposition of the eye's crystalline lens from its normal location. A partial dislocation of a lens is termed lens subluxation or subluxated lens; a complete dislocation of a lens is termed lens luxation or luxated lens. Image File history File linksMetadata Download high resolution version (2592x1944, 2229 KB) Summary Anterior lens luxation with associated rupture of the cornea in a Shih Tzu. ... Image File history File linksMetadata Download high resolution version (2592x1944, 2229 KB) Summary Anterior lens luxation with associated rupture of the cornea in a Shih Tzu. ... An eye is an organ of vision that detects light. ... Light from a single point of a distant object and light from a single point of a near object being brought to a focus by changing the curvature of the lens. ...

Although observed in humans, it is most commonly seen in dogs. Ciliary zonules normally hold the lens in place. Luxation can occur from trauma, cataract formation, glaucoma, or abnormal development of the zonules. With anterior lens luxation, the lens pushes into the iris or actually enters the anterior chamber of the eye. This can cause glaucoma, uveitis, or damage to the cornea. With posterior lens luxation, the lens falls back into the vitreous humour and lays on the floor of the eye. This type causes less problems than anterior lens luxation. Surgery is used to treat dogs with significant symptoms. Trinomial name Canis lupus familiaris (Linnaeus, 1758) This article is about the domestic dog. ... The zonule of Zinn is a ring of fibrous strands connecting the ciliary body with the crystalline lens of the eye. ... For the band with this name, see Cataract (band). ... The human iris The iris is the grey-brown area. ... The anterior chamber if the fluid-filled space inside the eye between the iris and the corneas innermost surface, the endothelium . ... Uveitis specifically refers to inflammation of the middle layer of the eye, termed the uvea but in common usage may refer to any inflammatory process involving the interior of the eye. ... The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber, providing most of an eyes optical power [1]. Together with the lens, the cornea refracts light and, as a result, helps the eye to focus. ... Vitreous humour is the clear aqueous solution that fills the space between the lens and the retina of the vertebrate eyeball. ...

Terrier breeds are predisposed to lens luxation, and it is probably inherited in the Sealyham Terrier, Jack Russell Terrier, Wirehaired Fox Terrier, and Tibetan Terrier.^[1] Notes Note The Sealyham Terrier is a dog breed, one of many Terrier breeds. ... The Jack Russell Terrier is a type of small terrier that has its origins in fox hunting. ... Common nickname Foxie Country of origin England Classification and breed standards The Wire Fox Terrier is a breed of dog, one of many terrier breeds. ... Country of origin Tibet Classification and breed standards The Tibetan Terrier is not a member of the terrier group, the name being given to it by European travelers to Tibet who were reminded of terriers from back home when they first encountered the breed. ...

Systemic associations

In humans, there are a number of systemic conditions that are associated with ectopia lentis^[2]:

More common:

• Marfan syndrome
• Homocystinuria
• Weill-Marchesani syndrome
• Sulfite oxidase deficiency
• Hyperlysinemia

Less common: Marfan syndrome is a connective tissue disorder characterized by unusually long limbs. ... Homocystinuria, also known as Cystathionine beta synthase deficiency, is inherited disorder of the metabolism of the amino acid methionine. ... Hyperlysinemia is a group of hereditary disorders characterized by an abnormal increase of lysine in the blood and associated with mental retardation, convulsions, and anemia. ...

• Ehlers-Danlos syndrome
• Crouzon disease
• Refsum syndrome
• Kniest syndrome
• Mandibulofacial dysostosis
• Sturge-Weber syndrome
• Conradi syndrome
• Pfaundler syndrome
• Pierre Robin syndrome
• Wildervanck syndrome
• Sprengel deformity

Ehlers-Danlos syndrome is a group of rare genetic disorders that diminish the bodys ability to make connective tissues. ... Crouzon Syndrome is a type of genetic disorder known as a branchial arch syndrome. ... Kniest dysplasia is an uncommon inherited disorder of bone growth. ... Treacher Collins syndrome (also known as Franceschetti-Zwahlen-Klein syndrome or mandibulofacial dysostosis) is a rare genetic disorder characterized by craniofacial deformities. ... To meet Wikipedias quality standards, this article or section may require cleanup. ...

References

See also

• List of eye diseases and disorders
• List of systemic diseases with ocular manifestations