In 1880, he founded the Sperry Electric Company in Chicago, Illinois to manufacture the electric dynamos and arc lamps that he had invented as a teenager. Over the next fifty years, he founded seven more companies to manufacture his own inventions, including:
The latter was founded to manufacture Sperry's development of the gyrocompass, originally invented by Herman Anschütz-Kaempfe in 1908. Sperry's first model was installed on USbattleship Delaware in 1911.