The endocannabinoid system (also endogenous cannabinoid system) consists of two transmembrane cannabinoid receptors, endogenous cannabinoids, a transporter protein (anandamide transporter), and the metabolic enzymes inactivating the endocannabinoids (MGL and FAAH). The CB1 receptors are present in many central and peripheral sites involved in the control of homeostasis [1]. CB2 receptors are primarily expressed in peripheral and immune tissues. The main endogenous cannabinoids are anandamide and 2-arachidonylglycerol. The Endogenous cannabinoid system affect a large number of physiologic processes including: feeding behavior, pain perception, motor control, memory and learning, immune and inflammatory responses, neuroprotection and intraocular pressure [1]. Transmembrane receptors are integral membrane proteins, which reside and operate typically within a cells plasma membrane, but also in the membranes of some subcellular compartments and organelles. ... The cannabinoid receptors are a class of receptors under the G-protein coupled receptor superfamily. ... ... Motto: Dayar Mongol Anthem: National Anthem of Mongolia Capital Ulaanbaatar Largest city Ulaanbaatar Official language(s) Mongolian Government President Prime minister Parliamentary democracy Nambaryn Enkhbayar Miyeegombyn Enkhbold Independence - Declared July 11, 1921 Area  â€¢ Total  â€¢ Water (%)   1,564,116 km² (18th) 0. ... It has been suggested that Fatty acyl amide hydrolase be merged into this article or section. ... Anandamide, also known as arachidonoylethanolamine or AEA, is a naturally occurring endogenous cannabinoid neurotransmitter found in the brain of animals, as well as other organs. ... Image:2-AG.png 2-Arachidonoylglycerol 2-Arachidonoylglycerol (2-AG) is an endogenous agonist of the CB1 receptor. ...

External links

• The Endocannabinoid System Network (ECSN) - A CME source about the Endocannabinoid System

References

1. Lambert, D. M.; Fowler, C. J. 2005. The Endocannabinoid System: Drug Targets, Lead Compounds, and Potential Therapeutic Applications J. Med. Chem. 48(16):5059-5087