Structural formula of enflurane

Enflurane (2-chloro-1,1,2,-trifluoroethyl-difluomethyl ether) is a halogenated ether that was commonly used for inhalational anesthesia during the 1970s and 1980s. Developed by Ross Terrell in 1963, it was first used clinically in 1966. Image File history File links Download high resolution version (1503x994, 17 KB) Summary Chemical structure of the anaesthetic enflurane, self made in ChemDraw and Photoshop by Ben. ... Image File history File links Download high resolution version (1503x994, 17 KB) Summary Chemical structure of the anaesthetic enflurane, self made in ChemDraw and Photoshop by Ben. ... A Halogenated Ether is a subcategory of a larger group of chemicals known as ethers. ... Cetacaine, a typical topical anesthetic Anesthesia (American English), also anaesthesia (British English), is the process of blocking the perception of pain and other sensations. ...

Enflurane is a structural isomer of isoflurane. It vaporizes readily, but is a liquid at room temperature. In chemistry, isomers are molecules with the same chemical formula and often with the same kinds of bonds between atoms, but in which the atoms are arranged differently. ... Isoflurane (1-chloro-2,2,2-trifluoroethyl difluoromethyl ether) is a halogenated ether used for inhalation anesthesia. ...

Clinically, enflurane produces a dose-related depression of myocardial contractility with an associated decrease in myocardial oxygen consumption. Between 2% and 5% of the inhaled dose is oxidised in the liver, producing fluoride ions and difluoromethoxy-difluoroacetic acid. This is significantly higher than the metabolism of its structural isomer isoflurane. Myocardium is the muscular tissue of the heart. ... Contractility is one of the factors which affect myocardial performance. ... A fluoride ion is the ionic form of fluorine. ... Isoflurane (1-chloro-2,2,2-trifluoroethyl difluoromethyl ether) is a halogenated ether used for inhalation anesthesia. ...

Physical properties