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Encyclopedia > Entamoeba histolytica
Entamoeba histolytica
Entamoeba histolytica cyst
Entamoeba histolytica cyst
Scientific classification
Domain: Eukaryota
Phylum: Amoebozoa
Class: Archamoebae
Genus: Entamoeba
Species: E. histolytica

For the infection and disease caused by this parasite, refer to Amoebiasis. Image File history File links Download high resolution version (2945x1979, 4748 KB)Chlorazol black stained sample revealing an Entamoeba histolytica cyst. ... For other uses, see Scientific classification (disambiguation). ... Kingdoms Eukaryotes are organisms with complex cells, in which the genetic material is organized into membrane-bound nuclei. ... Subgroups Mycetozoa(slime moulds) Archamoebae    Pelobiontida    Entamoebida Gymnamoebia Various others The Amoebozoa are a major group of amoeboid protozoa, including the majority that move by means of internal cytoplasmic flow. ... Genera Endolimax Entamoeba Mastigamoeba Mastigella Mastigina Pelomyxa Phreatamoeba The Archamoebae are a group of Amoebozoa distinguished by the absence of mitochondria. ... The entamoebae are a group of parasitic and commensal amoebae which lack mitochondria. ...


Entamoeba histolytica is an anaerobic parasitic protozoan, part of the genus Entamoeba. It infects predominantly humans and other primates. It is estimated that about 50 million people are infected with the parasite worldwide. Diverse mammals such as dogs and cats can become infected but are not thought to contribute significantly to transmission. The active (trophozoite) stage exists only in the host and in fresh loose feces; cysts survive outside the host in water, soils and on foods, especially under moist conditions on the latter. When cysts are swallowed they cause infections by excysting (releasing the trophozoite stage) in the digestive tract. Aerobic and anaerobic bacteria can be identified by growning them in liquid culture: 1: Obligate aerobic bacteria gather at the top of the test tube in order to absorb maximal amount of oxygen. ... Wikisource has an original article from the 1911 Encyclopædia Britannica about: Protozoa Protozoa (in Greek proto = first and zoa = animals) are single-celled eukaryotes (organisms whose cells have nuclei) that commonly show characteristics usually associated with animals, most notably mobility and heterotrophy. ... For other uses, see Genus (disambiguation). ... The entamoebae are a group of parasitic and commensal amoebae which lack mitochondria. ... This article does not cite its references or sources. ...


E. histolytica, as its name suggests (histolytic = tissue destroying), causes disease; infection can lead to amoebic dysentery or amoebic liver abscess. Symptoms can include fulminating dysentery, diarrhea, weight loss, fatigue, abdominal pain, and amebomas. The amoeba can actually 'bore' into the intestinal wall, causing lesions and intestinal symptoms, and it may reach the blood stream. From there, it can reach different vital organs of the human body, usually the liver, but sometimes the lungs, brain, spleen, etc. A common outcome of this invasion of tissues is a liver abscess, which can be fatal if untreated. Ingested red blood cells are sometimes seen in the amoeba cell cytoplasm. Dysentery is the inflammation of the intestine causing severe diarrhea. ... “Red cell” redirects here. ...


It can be diagnosed by stool samples but it is important to note that certain other species are impossible to distinguish by microscopy alone. Trophozoites may be seen in a fresh fecal smear and cysts in an ordinary stool sample. ELISA or RIA can also be used. Elisa (born Elisa Toffoli on 19 December 1977) is an Italian singer and solo artist, writing and performing within several genres, notably rock, blues, soul and ambient. ... Georges River, in the southern suburbs of Sydney (Australia) is a ria, or drowned river valley. ...


Genus and Species Entamoeba histolytica
Etiologic Agent of: Amoebiasis; Amoebic dysentery; Extraintestinal Amoebiasis, usually Amoebic Liver Abscess = “anchovy sauce”); Amoeba Cutis; Amoebic Lung Abscess (“liver-colored sputum”)
Infective stage Cyst
Definitive Host Human
Portal of Entry Mouth
Mode of Transmission Ingestion of mature cyst through contaminated food or water
Habitat Colon and Cecum
Pathogenic Stage Trophozoite
Locomotive apparatus Pseudopodia (“False Foot”)
Motility Active, Progressive and Directional
Nucleus 'Ring and dot' appearance: peripheral chromatin and central karyosome
Mode of Reproduction Binary Fission
Pathogenesis Lytic necrosis (it looks like “flask-shaped” holes in Gastrointestinal tract sections (GIT)
Type of Encystment Protective and Reproductive
Lab Diagnosis Most common is Direct Fecal Smear (DFS) and staining (but does not allow identification to species level); Enzymeimmunoassay (EIA); Indirect Hemagglutination (IHA); Antigen detection – monoclonal antibody; Polymerase Chain Reaction PCR for species identification. Culture: From faecal samples - Robinson's medium, Jones' medium
Treatment Metronidazole for the invasive trophozoites PLUS a lumenal amoebicide for those still in the intestine (Paromomycin is the most widely used)
Trophozoite Stage
Pathognomonic/Diagnostic Feature Ingested RBC; distinctive nucleus
Cyst Stage
Chromatoidal Body 'Cigar' shaped bodies (made up of crystalline ribosomes)
Number of Nuclei 1 in early stages, 4 when mature
Pathognomonic/Diagnostic Feature 'Ring and dot' nucleus and chromatoid bodies

Dysentery is an illness involving severe diarrhea that is often associated with blood in the feces. ... This article does not cite its references or sources. ... “PCR” redirects here. ... Metronidazole (INN) (IPA: ) is a nitroimidazole anti-infective drug used mainly in the treatment of infections caused by susceptible organisms, particularly anaerobic bacteria and protozoa. ... Paromomycin sulfate (brand name Humatin) is a drug that fights intestinal amoeba infection, or amebiasis. ...

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