Enterocyte is a type of epithelial cell of the superficial layer of the small and large intestine tissue. These cells can help breaking up molecules and transport them into the tissue. In zootomy, epithelium is a tissue composed of a layer of cells. ... Biological tissue is any substance made up of cells that perform a similar function within an organism. ...
Glucose, from the intestinal lumen, crosses the apical membrane of the enterocyte using the Na+ dependent glucose transporter; moves through the cytosol and exits the enterocyte via the basolateral membrane (into the blood capillary) using GLUT-2. Galactose uses the same transport system. Fructose, on the other hand, crosses the apical membrane of the enterocyte, using GLUT-5. It is thought to cross into the blood capillary using one of the other GLUT transporters.
Enterocyte is a type of epithelial cell of the superficial layer of the small and large intestine tissue.
Glucose, from the intestinal lumen, crosses the apical membrane of the enterocyte using the Na+ dependent glucose transporter; moves through the cytosol and exits the enterocyte via the basolateral membrane (into the blood capillary) using GLUT-2.
It is thought to cross into the blood capillary using one of the other GLUT transporters.
We are studying the differentiation process of the enterocyte, the cell that comprises 95% of all villus cells and is responsible for the nutrient digestion and absorption that is critical to life.
The enterocyte marker gene, intestinal alkaline phosphatase (IAP) is being used as a tool to identify and characterize transcription factors that mediate the differentiation process.
We have identified specific alterations in the phenotype of the enterocyte that appears to be a reliable marker for this gut mucosal failure and have ongoing studies that are geared toward an elucidation of this abnormal phentoype and the molecular events that cause it.
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