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Enterocyte - Wikipedia, the free encyclopedia (133 words) |
 | Enterocyte is a type of epithelial cell of the superficial layer of the small and large intestine tissue. |
 | Glucose, from the intestinal lumen, crosses the apical membrane of the enterocyte using the Na+ dependent glucose transporter; moves through the cytosol and exits the enterocyte via the basolateral membrane (into the blood capillary) using GLUT-2. |
 | It is thought to cross into the blood capillary using one of the other GLUT transporters. |
| Department of Surgery : Research : Massachusetts General Hospital (2945 words) |
 | We are studying the differentiation process of the enterocyte, the cell that comprises 95% of all villus cells and is responsible for the nutrient digestion and absorption that is critical to life. |
 | The enterocyte marker gene, intestinal alkaline phosphatase (IAP) is being used as a tool to identify and characterize transcription factors that mediate the differentiation process. |
 | We have identified specific alterations in the phenotype of the enterocyte that appears to be a reliable marker for this gut mucosal failure and have ongoing studies that are geared toward an elucidation of this abnormal phentoype and the molecular events that cause it. |