An epidemic is generally a widespread disease that affects many individuals in a population. An epidemic may be restricted to one locale or may even be global (pandemic). An outbreak of a disease is defined as being epidemic, however, not by how many members or what proportion of the population it infects but by how fast it is growing. When each infected individual is infecting more than one other individual, so that the number of infected individuals is growing exponentially, the disease is in an epidemic state. Thus even if the number of people affected is small, the phenomenon may still be called an epidemic, although for small epidemics the term "outbreak" is more often used.
For an epidemic state:
Where R0 is the basic reproduction number of the infection and S is the proportion of the population who are susceptible to the infection. This is merely a mathematical formalisation of the rule stated above.
Archangelsk region was traditionally referred to the regions of goitrous epidemy, which was primarily associated with biogeochemical characteristics, namely, with low iodine content in soil.
In the end of 1980s the problem of goitrous epidemy in the region became significantly aggravated, which was associated with the termination of iodine prophylaxis system existing in our country at the time.
The analysis of goitre prevalence, determined on the basis of external examination and palpation data, in different climatic geographical zones showed that goitre frequency, both in child and adolescence populations, increases in the direction from the north to the south of Archangelsk region.
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Epidemy of the Marburg strain of an African hemorrhagic fever in northern Angola