A bacteriostatic antimycobacterial prescribed to treat Tuberculosis (Mycobacterium). Bacteriostatic antibiotics hamper the growth of bacteria by interfering with bacteria protein production, interfering with bacteria DNA production interfering with bacteria cellular metabolism Bacteriostatic antibiotics inhibit growth and repoduction of the bacteria, though do not kill it, while bactericidal antibiotics kill bacteria. ... Tuberculous lungs show up on an X-ray image Tuberculosis is an infection with the bacterium Mycobacterium tuberculosis, which most commonly affects the lungs (pulmonary TB) but can also affect the central nervous system (meningitis), lymphatic system, circulatory system (miliary TB), genitourinary system, bones and joints. ... Species see text Mycobacterium is the a genus of actinobacteria, given its own family, the Mycobacteriaceae. ...
Ethambutol is indicated in patients with all forms of the pulmonary tuberculosis, in combination with rifampicin and isoniazid.
Ethambutol in adults is used orally in dose 25 mg per kg body weight, once per 24 h during the first two months of the treatment, followed by 15 mg per kg body weight/24 h, combined with isoniazid and rifampicin.
Ethambutol is an anti-tuberculosis medicine, acting by inhibition of the biosynthesis of the arabinogalactan and arabinomanan, due to inhibition of the decaprenil - R - arabinose activity.
Ethambutol diffuses into actively growing mycobacterium cells where it appears to inhibit their growth by preventing the synthesis of vital metabolites, thus causing impairment of cell metabolism arrest of multiplication and cell death.
Approximately 80% of an oral dose of ethambutol is absorbed from the gasto-intestinal tract, and the remainder is excreted unchanged in the faeces.
Ethambutol may produce optic neuritis which decreases visual acuity and which appears to be related to dose and duration of treatment.
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