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Encyclopedia > Ethylamphetamine
Ethylamphetamine
Systematic (IUPAC) name
N-ethyl-1-phenyl-propan-2-amine
Identifiers
CAS number 457-87-4
ATC code  ?
PubChem 9982
Chemical data
Formula C11H17N 
Mol. mass 163.259 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism hepatic
Half life  ?
Excretion renal
Therapeutic considerations
Pregnancy cat.

? IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ... PubChem is a database of chemical molecules. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... General Name, Symbol, Number carbon, C, 6 Chemical series nonmetals Group, Period, Block 14, 2, p Appearance black (graphite) colorless (diamond) Standard atomic weight 12. ... General Name, Symbol, Number hydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1, 1, s Appearance colorless Atomic mass 1. ... General Name, Symbol, Number nitrogen, N, 7 Chemical series nonmetals Group, Period, Block 15, 2, p Appearance colorless gas Standard atomic weight 14. ... The molecular mass (abbreviated MM) of a substance, formerly also called molecular weight and abbreviated as MW, is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... In pharmacology, bioavailability is used to describe the fraction of an administered dose of medication that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ... Drug metabolism is the metabolism of drugs, their biochemical modification or degradation, usually through specialized enzymatic systems. ... It has been suggested that Effective half-life be merged into this article or section. ... Excretion is the process of eliminating waste products of metabolism and other materials that are of no use. ... The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. ...

Legal status
Routes oral, intravenous, smoked, insufflated

N-ethylamphetamine (Etilamfetamine, Apetinil) is a stimulant drug derived from amphetamine which was invented in the early 1900s. The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ... In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ... Stimulants are drugs that temporarily increase alertness and wakefulness. ... Amphetamine or Amfetamine, also known as alpha-methyl-phenethylamine, phenyl-isopropylamine, beta-phenyl-isopropylamine, and benzedrine, is a prescription stimulant commonly used to treat Attention-deficit hyperactivity disorder (ADHD) in adults and children. ...


Ethylamphetamine was used as an appetite suppressant in the 1950s[1] but was not as commonly used as other amphetamine derivatives such as dexamphetamine or benzphetamine, and went out of fashion once newer drugs such as phenmetrazine were introduced. Anorectics, anorexigenics or appetite suppressants, are substances which reduce the desire to eat (anorectic, from the Greek an- = not and oreg- = extend, reach). Used on a short term basis clinically to treat obesity, some appetite suppressants are also available over the counter. ... Dextroamphetamine (also known as dextroamphetamine sulfate, dexamphetamine, dexedrine, Dexampex, Ferndex, Oxydess II, Robese, Spancap #1, and, informally, Dex), a stereoisomer of amphetamine, is an indirect-acting stimulant that releases norepinephrine from nerve terminals, thus promoting nerve impulse transmission. ... USA by Pharmacia. ... Phenmetrazine is an amphetamine-like drug. ...


Ethylamphetamine is intermediate between amphetamine and methamphetamine in potency, and is self-administered by animals;[2] concerns about its abuse potential were a likely factor that it was not so widely used as other similar drugs. Ethylamphetamine is still rarely encountered as a drug of abuse on the black market, but is relatively uncommon. This article is about the psychostimulant, d-methamphetamine. ...


References

  1. ^ Junet R. Ethylamphetamine in the treatment of obesity. Praxis. 1956 Oct 25;45(43):986-8. (French)
  2. ^ Woolverton WL, Shybut G, Johanson CE. Structure-activity relationships among some d-N-alkylated amphetamines. Pharmacology Biochemistry and Behavior. 1980 Dec;13(6):869-76.


 
 

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