 | | Etorphine | | Systematic (IUPAC) name | | 6,14-endoetheno – 7 a (1-(R)-hydroxy-1 methylbutyl)-tetrahydro-nororipavine | | Identifiers | | CAS number | 14521-96-1 | | ATC code | ? | | PubChem | ? | | Chemical data | | Formula | C25H33NO4 | | Mol. mass | 411.53 g/mol | | Pharmacokinetic data | | Bioavailability | ? | | Metabolism | ? | | Half life | ? | | Excretion | ? | | Therapeutic considerations | | Pregnancy cat. | ? IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ...
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General Name, symbol, number nitrogen, N, 7 Chemical series nonmetals Group, period, block 15, 2, p Appearance colorless gas Standard atomic weight 14. ...
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The molecular mass (abbreviated Mr) of a substance, formerly also called molecular weight and abbreviated as MW, is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ...
In pharmacology, bioavailability is used to describe the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ...
Drug metabolism is the metabolism of drugs, their biochemical modification or degradation, usually through specialized enzymatic systems. ...
The biological half-life of a substance is the time required for half of that substance to be removed from an organism by either a physical or a chemical process. ...
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The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. ...
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| | Routes | ? | Etorphine (Immobilon or M99) is a semi-synthetic opioid possessing an analgesic potency approximately 10,000 times that of morphine and was first prepared in 1960 from oripavine, which does not generally occur in opium poppy extract but rather in "poppy straw" and in related plants, Papaver orientale and Papaver bracteatum.[1] It was later reproduced in 1963 by a research group at McFarlan-Smith and Co. in Edinburgh, led by Professor Kenneth Bentley.[2][3] It can also be produced from thebaine. In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body. ...
An opioid is a chemical substance that has a morphine-like action in the body. ...
An analgesic (colloquially known as a painkiller) is any member of the diverse group of drugs used to relieve pain (achieve analgesia). ...
This article is about the drug. ...
Oripavine is an opiate and the major metabolite of thebaine. ...
Binomial name L. The opium poppy, Papaver somniferum, is the type of poppy from which opium and all refined opiates such as morphine, thebaine, codeine, papaverine, and noscapine are extracted. ...
Binomial name Papaver orientale (L.) The Oriental poppy (Papaver orientale) is a perennial poppy of the genus Papaver. ...
A minor constituent of opium, thebaine or paramorphine (C19H21NO3) is chemically similar to both morphine and codeine, but produces stimulatory rather than depressant effects. ...
Etorphine is most often used to immobilize elephants and other large mammals. Etorphine is only available legally for veterinary use and is strictly governed by law. Diprenorphine (M5050) is an opioid receptor antagonist that can be administered in proportion to the amount of etorphine used (1.3 times) to reverse its effects. Veterinary-strength etorphine is fatal to humans; one drop on the skin can cause death within a few minutes.[4] Genera and Species Loxodonta Loxodonta cyclotis Loxodonta africana Elephas Elephas maximus Elephas antiquus †Elephas beyeri †Elephas celebensis †Elephas cypriotes †Elephas ekorensis †Elephas falconeri †Elephas iolensis †Elephas planifrons †Elephas platycephalus †Elephas recki †Stegodon †Mammuthus †Elephantidae (the elephants) is a family of pachyderm, and the only remaining family in the order Proboscidea...
Veterinary medicine is the application of medical, diagnostic, and therapeutic principles to companion, domestic, exotic, wildlife, and production animals. ...
Diprenorphine (Revivon, M5050) is an opiate antagonist used to reverse the effects of the super-potent opioid analgesics such as etorphine and carfentanil that are used for tranquilizing large animals in veterinary medicine. ...
Large Animal Immobilon is a combination of etorphine plus acepromazine maleate. An etorphine antidote Large Animal Revivon contains mainly diprenorphine for animals and a human-specific naloxone-based antidote, which should be prepared prior to the etorphine. Acepromazine or Acetylpromazine is one of the phenothiazine derivative psychotropic drugs, used little in humans, however frequently in animals as a means of chemical restraint. ...
Diprenorphine (Revivon, M5050) is an opiate antagonist used to reverse the effects of the super-potent opioid analgesics such as etorphine and carfentanil that are used for tranquilizing large animals in veterinary medicine. ...
Naloxone is a drug used to counter the effects of opioid overdose, for example heroin and morphine overdose. ...
A close relative, dihydroetorphine has been used as an opioid painkiller for human usage in China. It is claimed to be less addictive than traditional opioids but this has yet to be confirmed. China is one of the only countries in the world to prescribe Dihydroetorphine, (a close relative of Etorphine) to humans. ...
Pharmacology
Etorphine is an agonist at μ, δ, and κ opioid receptors. It also has a weak affinity for the ORL1 nociceptin/orphanin FQ receptor.[5] The μ opioid receptors (MOR) are a class of opioid receptors with high affinity for enkephalins and beta-endorphin but low affinity for dynorphins. ...
δ-Opioid receptor activation produces analgesia. ...
κ-Opioid receptors are involved with analgesia, but activation also produces marked nausea and dysphoria. ...
Opioid receptors are a group of G-protein coupled receptors with opioids as ligands. ...
Opioid receptors are a group of G-protein coupled receptors with opioids as ligands. ...
Legal status In Hong Kong, Etorphine is regulated under Schedule 1 of Hong Kong's Chapter 134 Dangerous Drugs Ordinance. It can only be used legally by health professionals and for university research purporses. The substance can be given by pharmacists under a prescription. Anyone who supplies the substance without prescription can be fined $10000(HKD). The penalty for trafficking or manufacturing the substance is a $5,000,000 (HKD) fine and life imprisonment. Possession of the substance for consumption without license from the Department of Health is illegal with a $1,000,000 (HKD) fine and/or 7 years of jail time. ISO 4217 Code HKD User(s) Hong Kong Inflation 2. ...
In the Netherlands, Etorphine is a list I drug of the Opium Law. It is only used for veterinary purposes in zoos to immobilise large animals.
In the US, Etorphine is listed as a Schedule I drug, although Etorphine hydrochloride is classified as Schedule II. In chemistry, hydrochlorides are salts resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic base (mostly amines). ...
References - ^ Opium: the king of narcotics
- ^ Bentley KW, Hardy DG. "New potent analgesics in the morphine series." Proceedings of the Chemical Society. 1963;220.
- ^ Bentley KW, Hardy DG. "Novel analgesics and molecular rearrangements in the morphine-thebaine group. 3. Alcohols of the 6,14-endo-ethenotetrahydrooripavine series and derived analogs of N-allylnormorphine and -norcodeine." Journal of the American Chemical Society. 1967 Jun 21;89(13):3281-92. PMID 6042764
- ^ Zoo Vet At Large - Sky Travel (8 July 2007, Part 10 of 26)
- ^ Hawkinson JE, Acosta-Burruel M, Espitia SA. "Opioid activity profiles indicate similarities between the nociceptin/orphanin FQ and opioid receptors." European Journal of Pharmacology. 2000 Feb 18;389(2-3):107-14. PMID 10688973
Sky Travel is a channel from BSkyB that shows extensive programmes about travel, adverts for travel agencies, and documentries. ...
is the 189th day of the year (190th in leap years) in the Gregorian calendar. ...
Year 2007 (MMVII) was a common year starting on Monday of the Gregorian calendar in the 21st century. ...
External links - Opioids.com page on etorphine
- Etorphine: Molecule of the Month
| Opioids (N02A) | | Opiate
derivatives | | Whole Opium
Preparations | Dover's Powder • Granulated Opium • Laudanum • Mithridate • Opium • Paregoric • Poppy Straw Concentrate • Poppy tea • Powdered Opium • Raw Opium • Smoking Opium An opioid is a chemical substance that has a morphine-like action in the body. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
For other uses see Opiate (disambiguation), or for the class of drugs see Opioid. ...
This article is about the medicine. ...
Elaborately-gilded drug jar for storing mithridate. ...
This article is about the drug. ...
Paregoric, or camphorated tincture of opium, is a medication known for its antidiarrheal, antitussive, and analgesic properties. ...
Dried poppy pods and seeds Poppy tea is a narcotic analgesic tea which is brewed from the dried parts of the Papaver somniferum plant. ...
| | | Natural Opiates | Codeine • Morphine • Narceine • Noscapine • Omnopon • Oripavine • Pantopon • Papaveretum • Pseudomorphine • Tetrapon • Thebaine For the band, see Codeine (band). ...
This article is about the drug. ...
Noscapine (also known as Narcotine) is an opioid agonist without significant analgesic properties [1]. It is grouped as part of the benzylisoquinolines, of which papaverine is also included. ...
Papaveretum (BAN) is a preparation containing a mixture of hydrochloride salts of opium alkaloids. ...
Oripavine is an opiate and the major metabolite of thebaine. ...
Pantopon is a preparation of opiates made up of all of the alkaloids present in opium in their natural proportions as hydrochloride salts . ...
Papaveretum (BAN) is a preparation containing a mixture of hydrochloride salts of opium alkaloids. ...
A minor constituent of opium, thebaine or paramorphine (C19H21NO3) is chemically similar to both morphine and codeine, but produces stimulatory rather than depressant effects. ...
| | | Semisynthetics | 2,4-Dinitrophenylmorphine • 14-Hydroxyazidomorphine • 14-Ethoxymetopon • 14-Methoxymetopon • 14-Phenylpropoxymetopon • 6-Ketonalbuphine • 6-Methyldihydromorphine • 6-Methylenedihydrodesoxymorphine • 6-Methylene-14-hydroxydihydrodesoxymorphine • 8,14-Dihydroxydihydromorphinone • Acetylcodeine • Acetyldihydrocodeine • Acetylmorphone • Azidocodeine • Azidomorphine • Benzylmorphine • Chloromorphide • Clocinnamox • Codeine • Codeinone • Codorphone • Codoxime • Desocodeine • Desomorphine • Diacetyldihydromorphine • Dihydrocodeine • Dihydrocodeinone enol acetate • Dihydrohydroxycodeinone • Dihydrodesoxymorphine • Dihydroheroin • Dihydroheterocodeine • Dihydroisocodeine • Dihydromorphine • Dibutanoylmorphine • Dipropanoylmorphine • Ethyldihydromorphinone • Ethyldihydromorphine • Ethylmorphine • Heroin (Diamorphine) • Heroin-7,8-Oxide • Heterocodeine • Hydrocodone • Hydromorphinol • Hydromorphone • Isocodeine • Methyldesorphine • Methyldihydromorphine • Methylnaltrexone • Metopon • Morphinone • Myrophine • N-Phenethyl-14-ethoxymetopon • Nalbuphine • Nalfurafine • Nalmefene • Nalodeine • Nalorphine • Naloxone • Naltrexone • Naltrindole • Nicocodeine • Nicodicodeine • Nicomorphine • Oxycodone • Oxymorphone • Pholcodine • Semorphone • Thebacon 6-Methylenedihydrodesoxymorphine (6-MDDM) is an opiate analogue that is a derivative of hydromorphone, where the 6-ketone group has been replaced by methylene. ...
Acetyldihydrocodeine is an opiate derivative developed as a cough suppressant and analgesic. ...
Acetylmorphone (Dihydromorphinone acetate) is an opiate analogue that is an acetylated derivative of hydromorphone which was developed in the early 1900s as a potential cough suppressant and analgesic. ...
This article needs additional references or sources to facilitate its verification. ...
For the band, see Codeine (band). ...
Codeinone is a strong Opiod. ...
Diacetyldihydromorphine (Paralaudin, Dihydroheroin) is a potent opiate derivative which is rarely used in some countries for the treatment of strong pain such as that caused by terminal cancer, as a more potent form of diamorphine. ...
Dihydrocodeine, also called DHC, Drocode, Paracodeine and Parzone and by the brand names of Synalgos DC, Panlor DC, Panlor SS, SS Bron, Drocode, Paracodin, Codidol, Didor Continus, Dicogesic, Codhydrine, Dekacodin, DH-Codeine, Didrate, Dihydrin, Hydrocodin, Nadeine, Novicodin, Rapacodin, Fortuss, Dico, and DF-118 amongst others, is a semi-synthetic opioid...
The chemical structure of dihydrocodeinone enol acetate Dihydrocodeinone Enol Acetate, or Thebacon, formerly marketed as its hydrochloride salt under the trade name Acedicon, is a semisynthetic opioid once used as an antitussive, primarily in Europe. ...
Not to be confused with oxytocin. ...
Diacetyldihydromorphine (Paralaudin, Dihydroheroin) is a potent opiate derivative developed in Germany in 1929 which is rarely used in some countries for the treatment of strong pain such as that caused by terminal cancer, as a more potent form of diamorphine. ...
Dihydromorphine is a semi-synthetic opioid invented in Germany in the first years of the twentieth century. ...
Dipropanoylmorphine is the 3,6-dipropanoyl ester of morphine, CAS number 10589-79-4. ...
Ethylmorphine is a drug in the class of both opiates (representing a minor synthetic change from morphine) and opioids (being effective in the CNSs opioid reception system) . Its effects in humans mainly stem from its metabolic conversion to morphine. ...
For other uses, see Heroin (disambiguation). ...
Heterocodeine (6-methylmorphine) is an opiate derivative, the 6-methyl ether of morphine, and a structural isomer of codeine. ...
Hydrocodone or dihydrocodeinone is a semi-synthetic opioid derived from two of the naturally occurring opiates, codeine and thebaine. ...
Hydromorphone is a drug developed in Germany in the 1920s and introduced to the mass market beginning in 1926. ...
Methylnaltrexone (MTNX) is one of the newer agents of peripherally-acting μ-opioid antagonists that act to reverse some of the side effects of opioid drugs such as constipation without affecting analgesia or precipitating withdrawals. ...
Metopon (5-methylhydromorphone hydrochloride) is an opiate analogue that is a methylated derivative of hydromorphone which was invented in 1948 as an analgesic. ...
Morphinone is a very strong Opiod. ...
Nalbuphine (nalbuphine hydrochloride) is a synthetic opioid used commercially as an analgesic under a variety of trade names, including Nubain. ...
Nalmefene (Revex) is an opioid receptor antagonist used primarily in the management of alcohol dependence, and also has been investigated for the treatment of other addictions such as pathological gambling and addiction to shopping. ...
Nalorphine (INN, also known as N-allyl-normorphine) is a narcotic antagonist. ...
Naloxone is a drug used to counter the effects of opioid overdose, for example heroin and morphine overdose. ...
Naltrexone is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence. ...
Naltrindole is a highly potent, highly selective delta opioid receptor antagonist used in biomedical research. ...
Nicocodeine (Lyopect) is an opiate derivative developed as a cough suppressant and analgesic. ...
Nicodicodeine is an opiate derivative developed as a cough suppressant and analgesic. ...
Nicomorphine (Vilan) is the 3,6-dinicotinate ester of morphine. ...
Not to be confused with oxytocin. ...
Oxymorphone (Opana, Numorphan) or 14-Hydroxydihydromorphinone is a powerful semi-synthetic opioid analgesic that is derived from thebaine, and is approximately 6–8 times more potent than morphine. ...
Pholcodine is a drug which is an opioid cough suppressant (antitussive). ...
Semorphone (Mr 2264) is an opiate analogue that is an N-substituted derivative of oxymorphone. ...
The chemical structure of dihydrocodeinone enol acetate Dihydrocodeinone Enol Acetate, or Thebacon, formerly marketed as its hydrochloride salt under the trade name Acedicon, is a semisynthetic opioid once used as an antitussive, primarily in Europe. ...
| | | Opiate metabolites | Codeine-N-Oxide • Morphine-3-glucuronide • Morphine-6-glucuronide • Monoacetylmorphine • Morphine-N-Oxide • Naltrexol • Norcodeine • Normorphine Morphine-6-glucuronide (M6G) is of more than simply academic interest, since it is the major active metabolite of morphine, and as such is the molecule responsible for much of the pain-relieving effects of morphine (and heroin and codeine). ...
6-monoacetylmorphine (6-MAM) is one of 2 active metabolites of heroin (diacetylmorphine), the other being the much less active 3-monoacetylmorphine (3-MAM). ...
| | | | Morphinans | Aknadinine • Butorphanol • Cyclorphan • Cyprodime • Dextro-3-hydroxy-N-allylmorphinan • Dextromethorphan • Dextrorphan • Dimemorfan • Drotebanol • Levargorphan • Levallorphan • Levorphanol • Levorphan • Levophenacylmorphan • Levomethorphan • Norlevorphanol • Oxilorphan • Phenomorphan • Racemethorphan • Racemorphan • Salutaridine (Sinoacutine) • Sinococuline • Sinomenine (Cocculine) Morphinan is the base chemical structures of a subgroup of opioids. ...
Butorphanol (INN) is a morphinan-type synthetic opioid analgesic marketed in the U.S. under the trade name Stadol. ...
Dextromethorphan (DXM or DM) is an antitussive (cough suppressant) drug found in many over-the-counter cold and cough medicines. ...
Dextrorphan is a pharmacologically active metabolite of Dextromethorphan (DXM). ...
Dimemorfan is a cough suppressant. ...
Levorphanol is an opioid medication used to treat severe pain. ...
Levomethorphan is an optical isomer of dextromethorphan. ...
Oxilorphan is an opioid antagonist from the morphinan family of drugs. ...
Phenomorphan is an opioid analgesic. ...
Racemethorphan is a racemic mixture of the stereoisomers of methorphan , namely dextromethorphan , which is the active ingredient in DM cough syrups , and the lesser known levomethorphan which is described as a controlled substance in The Merck Index - likely because it has more potential for abuse than its dextro enantiomer . ...
| | | Benzomorphans | 5,9-DEHB • Anazocine • Bremazocine • Cogazocine • Cyclazocine • Dezocine • Eptazocine • Etazocine • Ethylketocyclazocine • Fluorophen • Ketazocine • Metazocine • Pentazocine • Phenazocine • Quadazocine • Thiazocine Cyclazocine is a mixed opiate agonist-antagonist. ...
Dezocine (Dalgan, WY-16225) is an opioid analgesic related to pentazocine, with a similar profile of effects that include analgesic action and euphoria at low doses,[1] but produces dysphoria and hallucinations at high doses, most likely due to action at κ-opioid receptors. ...
Ketazocine (INN) is a cyclazocine derivative used in opioid receptor research. ...
Metazocine is an opioid analgesic related to pentazocine. ...
Pentazocine is a synthetically-prepared narcotic (opioid analgesic) drug used to treat mild to moderately severe pain. ...
Phenazocine (Prinadol, Narphen) is an opioid analgesic, invented in the 1950s,[1][2] which is related to pentazocine and has a similar profile of effects that include analgesic action and euphoria, but may produce dysphoria and hallucinations at high doses, most likely due to action at κ-opioid and σ receptors. ...
| | | 4-Phenylpiperidines | | | Allylnorpethidine • Anileridine • Benzethidine • Carperidine • Difenoxin • Diphenoxylate • Etoxeridine (Carbetidine) • Furethidine • Hydroxypethidine (Bemidone) • Hydroxymethoxypethidine • Morpheridine • Oxpheneridine (Carbamethidine) • Meperidine-N-Oxide • Pethidine (Meperidine) • Pethidine Intermediate A • Pethidine Intermediate B (Norpethidine) • Pethidine Intermediate C (Pethidinic Acid) • Pheneridine • Phenoperidine • Piminodine • Properidine (Ipropethidine) • Sameridine Pethidine (INN) or meperidine (USAN) (also referred to as: isonipecaine; lidol; pethanol; piridosal; Algil®; Alodan®; Centralgin®; Demerol®; Dispadol®; Dolantin®; Dolargan® (in Poland);[1] Dolestine®; Dolosal®; Dolsin®; Mefedina®) is a fast-acting opioid analgesic drug. ...
Anileridine (Leritine®) is a synthetic opioid and strong analgesic medication. ...
Benzethidine is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine). ...
Carperidine is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine). ...
Difenoxin (Motofen) is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine). ...
On opiod agonist used for the treatment of diarrhea. ...
Etoxeridine (Carbetidine, Atenos) is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine). ...
Furethidine is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine). ...
Hydroxypethidine (Bemidone) is an opioid analgesic that is an analogue of pethidine (meperidine). ...
Morpheridine is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine). ...
Oxpheneridine (Carbamethidine) is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine). ...
Pethidine (INN) or meperidine (USAN) (also referred to as: isonipecaine; lidol; pethanol; piridosal; Algil®; Alodan®; Centralgin®; Demerol®; Dispadol®; Dolantin®; Dolargan® (in Poland);[1] Dolestine®; Dolosal®; Dolsin®; Mefedina®) is a fast-acting opioid analgesic drug. ...
Pethidine Intermediate A is a 4-phenylpiperidine derivative that is a precursor to the opioid analgesic drug pethidine (meperidine). ...
Norpethidine (Normeperidine, Pethidine Intermediate B) is a 4-phenylpiperidine derivative that is both a metabolite of and a precursor to pethidine (meperidine). ...
Pethidinic Acid (Meperidinic Acid, Pethidine Intermediate C) is a 4-phenylpiperidine derivative that is both a metabolite of and a precursor to pethidine (meperidine). ...
Pheneridine is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine). ...
Phenoperidine is an opiod general anesthetic. ...
Piminodine (Alvodine) is an opioid analgesic that is an analogue of pethidine (meperidine). ...
Properidine is an opiate analgesic and the isopropyl analog of Meperidine. ...
Sameridine is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine). ...
| | | Prodines | Allylprodine • α-meprodine • α-prodine • β-meprodine • β-prodine • Isopromedol • Meprodine • MPPP • PEPAP • Prodine • Prosidol • Trimeperidine (Promedol) Prodine (Prisilidine, Nisentil) is an opioid analgesic that is an analogue of pethidine (meperidine). ...
Allylprodine is an opioid analgesic that is an analogue of prodine. ...
Meprodine is an opioid analgesic that is an analogue of pethidine (meperidine). ...
Prodine (Prisilidine, Nisentil) is an opioid analgesic that is an analogue of pethidine (meperidine). ...
Meprodine is an opioid analgesic that is an analogue of pethidine (meperidine). ...
Prodine (Prisilidine, Nisentil) is an opioid analgesic that is an analogue of pethidine (meperidine). ...
Meprodine is an opioid analgesic that is an analogue of pethidine (meperidine). ...
MPPP (1-methyl 4-phenyl 4-propionoxypiperidine) is an opioid analgesic drug. ...
PEPAP is an opioid analgesic that is an analogue of pethidine (meperidine). ...
Prodine (Prisilidine, Nisentil) is an opioid analgesic that is an analogue of pethidine (meperidine). ...
Prosidol is an opioid analgesic that is an analogue of prodine. ...
Trimeperidine (Promedol) is an opioid analgesic that is an analogue of prodine. ...
| | | | Acetoxyketobemidone • Droxypropine • Ketobemidone • Methylketobemidone • Propylketobemidone Ketobemidone structure Ketobemidone is a powerful opioid analgesic. ...
Acetoxyketobemidone (O-Acetylketobemidone) is an opioid analgesic that is an acetylated derivative of ketobemidone. ...
Droxypropine is a cough suppressant. ...
Ketobemidone structure Ketobemidone is a powerful opioid analgesic. ...
Methylketobemidone is an opioid analgesic that is an analogue of ketobemidone. ...
Propylketobemidone is an opioid analgesic that is an analogue of ketobemidone. ...
| | | Others | | | | Open Chain
Opioids | | Amidones | Dextromethadone • Dipipanone • Hexalgon (Norpipanone) • Isomethadone • Levomethadone • Methadone • Methadone intermediate • Normethadone • Norpipanone • Phenadoxone (Heptazone) • Pipidone Alvimopan (Entereg) is a drug which behaves as a peripherally acting μ-opioid antagonist. ...
Imodium redirects here. ...
Picenadol (LY-150720) is a 4-phenylpiperidine derivative that is an opioid analgesic drug. ...
Dipipanone hydrochloride is an opioid painkiller. ...
Methadone (Dolophine, Amidone, Methadose, Physeptone, Heptadon and many others) is a synthetic opioid, used medically as an analgesic, antitussive and a maintenance anti-addictive for use in patients on opioids. ...
Normethadone is a cough suppressant. ...
Phenadoxone (Heptalgin®) is an opioid analgesic of the open chain class (methadone and relatives) invented in Germany in 1947. ...
| | | Methadols | Acetylmethadol • α-methadol • α-acetylmethadol • β-methadol • β-acetylmethadol • Dimepheptanol (Racemethadol) • Levo-α-acetylmethadol • Noracymethadol Levomethadyl acetate, also known as levo-α-acetylmethadol (LAAM) is a synthetic opioid similar in structure to methadone. ...
| | | Moramides | Dextromoramide • Levomoramide • Moramide intermediate • Racemoramide Dextromoramide (Palfium®, Palphium®, Jetrium®, Dimorlin®) is the right-handed isomer of the moramide molecule. ...
| | | Thiambutenes | Thiambutene • Diethylthiambutene • Dimethylthiambutene • Ethylmethylthiambutene • Tipepidine Diethylthiambutene (N,N-Diethyl-1-methyl-3,3-di-2-thienylallylamine, Diethibutin, Themalon) is an opioid analgesic drug which was mainly used in veterinary medicine. ...
Dimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, Dimethibutin, Ohton) is an opioid analgesic drug. ...
Ethylmethylthiambutene (N-ethyl-N-methyl-1-methyl-3,3-di-2-thienylallylamine, Emethibutin) is an opioid analgesic drug. ...
Tipepidine is a cough suppressant. ...
| | | Phenalkoxams | Dextropropoxyphene • Dimenoxadol • Dioxaphetyl Butyrate • Levopropoxyphene • Propoxyphene Dextropropoxyphene is an analgesic in the opioid category. ...
Dimenoxadol (Estocin) is an opioid analgesic which is a diphenylacetic acid derivative, related to other drugs such as dextropropoxyphene. ...
Dioxaphetyl Butyrate (Amidalgon, Spasmoxal) is an opioid analgesic which is a diphenylacetic acid derivative, related to other drugs such as dextropropoxyphene. ...
The structure of Levopropoxyphene Levopropoxyphene is an antitussive. ...
Dextropropoxyphene is an analgesic in the opioid category that is used to treat severe pain and severe coughs. ...
| | | Ampromides | Diampromide • Phenampromide • Propiram Diampromide is an opioid analgesic from the ampromide family of drugs, related to other drugs such as propiram. ...
Phenampromide is an opioid analgesic from the ampromide family of drugs, related to other drugs such as propiram and diampromide. ...
Propiram (Algeril) is an opioid analgesic from the ampromide family of drugs. ...
| | | Others | IC-26 • Lefetamine • R-4066 Lefetamine is a psychoactive drug which has effects similar to both morphine and methylphenidate. ...
| | | | Anilidopiperidines | 3-Allylfentanyl • 3-Methylfentanyl • 3-Methylthiofentanyl • Alfentanil • α-methylacetylfentanyl • α-methylfentanyl • α-methylthiofentanyl • Benzylfentanyl • β-hydroxyfentanyl • β-hydroxythiofentanyl • β-methylfentanyl • Brifentanil • Carfentanil • Fentanyl • Lofentanil • Mirfentanil • Ohmefentanyl • Parafluorofentanyl • Phenaridine • Remifentanil • Sufentanil • Thenylfentanyl • Thiofentanyl • Trefentanil 3-Allylfentanyl is an opioid analgesic that is an analogue of fentanyl. ...
3-Methylfentanyl (3-MF, mefentanyl) is an opioid analgesic that is an analogue of fentanyl. ...
3-methyl-thiofentanyl is an opioid analgesic that is an analogue of fentanyl. ...
Alfentanil (Alfenta) is a parenteral short-acting opioid painkiller, used for anaesthesia in surgery. ...
α-methylacetylfentanyl is an opioid analgesic that is an analogue of fentanyl. ...
α-methylfentanyl is an opioid analgesic that is an analogue of fentanyl. ...
α-methyl-thiofentanyl is an opioid analgesic that is an analogue of fentanyl. ...
β-hydroxyfentanyl is an opioid analgesic that is an analogue of fentanyl. ...
β-hydroxythiofentanyl is an opioid analgesic that is an analogue of fentanyl. ...
β-Methylfentanyl is an opioid analgesic that is an analogue of fentanyl. ...
Brifentanil (A-3331) is an opioid analgesic that is an analogue of fentanyl and was developed in the early 1990s. ...
Carfentanil, also Carfentanyl, is an analogue of the popular opioid Fentanyl, and is currently the most potent opioid known [Actually Ohmefentanil is 13,000X morphine]. It has a quantitative potency approximately 10,000 times that of morphine and 100 times that of fentanyl (activity in humans starting at about 1...
Fentanyl is an opioid analgesic, first synthesized by Janssen Pharmaceutica (Belgium) in the late 1950s, with a potency many times that of morphine. ...
Lofentanil is an opioid analgesic that is an analogue of fentanyl and was developed in the early 1980s. ...
This article or section is not written in the formal tone expected of an encyclopedia article. ...
Para-fluorofentanyl is an opioid analgesic that is an analogue of fentanyl. ...
Phenaridine (2,5-Dimethylfentanyl) is an opioid analgesic that is an analogue of fentanyl. ...
Remifentanil is a potent ultra short-acting synthetic opioid analgesic drug. ...
Sufentanil is a synthetic opioid analgesic drug approximately 5 to 10 times more potent than fentanyl. ...
Thiofentanyl is an opioid analgesic that is an analogue of fentanyl. ...
Trefentanil (A-3665) is an opioid analgesic that is an analogue of fentanyl and was developed in the early 1990s. ...
| | Oripavine
derivatives | 7-PET • Acetorphine • Alletorphine • BU-48 • Buprenorphine • Cyprenorphine • Dihydroetorphine • Diprenorphine • Etorphine • N-cyclopropylmethyl-noretorphine • Nepenthone • Norbuprenorphine • Thevinone • Thienorphine Oripavine is an opiate and the major metabolite of thebaine. ...
7-PET is a potent analgesic drug, several thousand times stronger than morphine by weight. ...
Acetorphine is a potent analgesic drug (painkiller), several thousand times stronger than morphine by weight. ...
Buprenorphine, is an opioid drug with partial agonist and antagonist actions. ...
Cyprenorphine (M-285) is a drug which is an opioid derivative. ...
China is one of the only countries in the world to prescribe Dihydroetorphine, (a close relative of Etorphine) to humans. ...
Diprenorphine (Revivon, M5050) is an opiate antagonist used to reverse the effects of the super-potent opioid analgesics such as etorphine and carfentanil that are used for tranquilizing large animals in veterinary medicine. ...
Buprenorphine, also colloquially referred to as bupe, is an opioid drug with partial agonist and antagonist actions. ...
| | | Phenazepines | Ethoheptazine • Meptazinol • Metheptazine • Metethoheptazine • Proheptazine Ethoheptazine (Zactane, Equagesic) is an opioid analgesic from the phenazepine family. ...
Meptazinol is an opioid analgesic for use with moderate to severe pain, most commonly used to treat pain in obstetrics (childbirth). ...
Metheptazine is an opioid analgesic from the phenazepine family. ...
Metethoheptazine (WY-535) is an opioid analgesic from the phenazepine family. ...
Proheptazine is an opioid analgesic from the phenazepine family. ...
| | | Pirinitramides | Bezitramide • Piritramide Bezitramide (4-[4-(2-oxo-3-propanoyl-benzoimidazol-1-yl)-1-piperidyl]-2,2-diphenyl-butanenitrile MW: 492. ...
Piritramide (Dipidolor®) is a synthetic opioid analgesic with about 65-75 percent of the mg-for-mg strength of morphine. ...
| | | Benzimidazoles | Clonitazene • Etonitazene Benzimidazole is a heterocyclic aromatic organic compound. ...
Clonitazene is an opioid analgesic. ...
Etonitazene is a highly potent narcotic analgesic (1000-1500x morphine). ...
| | | Indoles | 7-Acetoxymitragynine • 7-Hydroxymitragynine • Akuammidine • Akuammine • Eseroline • Ibogaine • Mitragynine • ψ-Akuammigine Indole is an aromatic heterocyclic organic compound. ...
7-hydroxymitragynine, an indole, is an active alkaloid in the plant Mitragyna speciosa, commonly known as Kratom. ...
Ibogaine is an indole alkaloid, a long-acting hallucinogen which has gained attention due to its application in the treatment of opioid addiction and similar addiction syndromes. ...
Mitragynine, an indole, is the dominant alkaloid in the Mitragina specosia plant. ...
| | | Diphenylmethylpiperazines | BW373U86 • DPI-221 • DPI-287 • DPI-3290 • SNC-80 SNC-80 is an opioid analgesic drug used in scientific research. ...
| | | Opioid Peptides | Casomorphin • DADLE • DALDA • DAMGO • Dermenkephalin • Dermorphin • Deltorphin • DPDPE • Dynorphin • Endomorphin • Endorphin • Enkephalin • TRIMU 5 Casomorphin is a peptide sequence that is derived from a protein found in milk called casein, and which some people consider to be addictive to humans and cause an opiate effect. ...
This article does not cite its references or sources. ...
Dynorphin (Dyn) is a popular and powerful opioid ligand. ...
Runners high redirects here. ...
For other uses, see Endorphin (disambiguation). ...
Endorphins are endogenous opioid biochemical compounds. ...
TRIMU 5 is a selective agonist of the mu-2 mu opioid receptor. ...
| | | Others | 4-(p-Bromophenyl)-4-(dimethylamino)-1-phenethylcyclohexanol • C-8813 • Ciramadol • Enadoline • Faxeladol • Herkinorin • JTC-801 • Methopholine • NNC 63-0532 • Noscapine/Narcotine • O-Desmethyltramadol • Salvinorin A • RWJ-394,674 • Tapentadol • Tifluadom • Tilidine • Tramadol • Viminol • W-18 • Zipeprol Ciramadol (WY-15705) is an opioid analgesic that was developed in the late 1970s. ...
Faxeladol is an opioid analgesic. ...
Herkinorin is an opioid analgesic that is an analogue of the natural product Salvinorin A. It was discovered in 2005 during structure-activity relationship studies into neoclerodane diterpenes, the family of chemical compounds of which Salvinorin A is a member. ...
Methopholine is an opioid analgesic drug invented in the 1960s. ...
Noscapine (also known as Narcotine) is an opioid agonist without significant analgesic properties [1]. It is grouped as part of the benzylisoquinolines, of which papaverine is also included. ...
O-Desmethyltramadol (M1) is an opioid analgesic which is made in the body from tramadol. ...
Salvinorin A is the main active psychotropic constituent of the plant Salvia divinorum (diviners sage, Mexican mint). ...
Tapentadol (INN) is a centrally-acting analgesic with a unique dual mode of action as an agonist at the μ-opioid receptor and as a norepinephrine reuptake inhibitor. ...
Tifluadom is a benzodiazepine derivative with an unusual activity profile. ...
Tilidine (INN, USAN), or tilidate (BAN) (Valoron®, Valtran®, Tilidin) is a synthetic opioid analgesic, used for treatment of moderate to severe pain, both acute and chronic[1]. Considered a low- to medium-potency opioid, it has the oral potency of about 0. ...
Tramadol (INN) (IPA: ) is an atypical opioid which is a centrally acting analgesic, used for treating moderate to severe pain. ...
Zipeprol is a cough suppressant. ...
| | | Narcotic Antagonists | 5'-Guanidinonaltrindole • β-Funaltrexamine • Binaltorphimine • Cyclazocine • Cyclohexyl-alpha-phenethylallylamine • Diprenorphine • M5050 • Levallorphan • Nalmefene • Naloxazone • Naloxonazine • Naloxone • Nalorphine • Naltrexone • Naltrindole • Norbinaltorphimine • Oxilorphan Cyclazocine is a mixed opiate agonist-antagonist. ...
Diprenorphine (Revivon, M5050) is an opiate antagonist used to reverse the effects of the super-potent opioid analgesics such as etorphine and carfentanil that are used for tranquilizing large animals in veterinary medicine. ...
Nalmefene (Revex) is an opioid receptor antagonist used primarily in the management of alcohol dependence, and also has been investigated for the treatment of other addictions such as pathological gambling and addiction to shopping. ...
Naloxone is a drug used to counter the effects of opioid overdose, for example heroin and morphine overdose. ...
Nalorphine (INN, also known as N-allyl-normorphine) is a narcotic antagonist. ...
Naltrexone is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence. ...
Naltrindole is a highly potent, highly selective delta opioid receptor antagonist used in biomedical research. ...
Oxilorphan is an opioid antagonist from the morphinan family of drugs. ...
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