Eugene V. Koonin (PhD) is an expert in the field of biotechnology.
Credentials: Senior Investigator, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA MS (1978) and PhD (1983) in Molecular Biology from Department of Biology, Moscow State University, Moscow, Russia. Research in Computational Biology in Institute of Poliomyelitis and Institute of Microbiology, Moscow (Russia) in 1985-1991. Research in Computational Biology and Genomics at NCBI since 1991. Editor of Genome Analysis section in Trends in Genetics.
Principal research goals:
Comparative analysis of sequenced genomes and automatic methods for genome-scale annotation of gene functions.
Application of comparative genomics for phylogenetic analysis, reconstruction of ancestral life forms and building large-scale evolutionary scenarios.
Mathematical modeling of genome evolution.
Computational study of the major transitions in the evolution of life, such as the origin of eukaryotes.
Evolution of eukaryotic signaling and developmental pathways from the comparative-genomic perspective.
Testing fundamental predictions of the theory of evolution using genome-wide sequence comparison.
Glazko GV, Koonin EV, Rogozin IB (2004) Mutation hotspots in the p53 gene in tumors of different origin: correlation with evolutionary conservation and signs of positive selection.
Kondrashov FA, Koonin EV (2004) A common framework for understanding the origin of genetic dominance and evolutionary fates of gene duplications.
Koonin EV (2003) Comparative genomics, minimal gene-sets and the last universal common ancestor.
Feeds |
Contact