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Encyclopedia > Fertility medication

Fertility medication may in a larger sense include any medication that enhances fertility, but in a specific sense consists of agents that stimulate follicle development of the ovary. It is a variant of assisted reproductive technology. Fertility is the natural capability of giving life. ... Ovarian follicles or Graafian follicles (after Regnier de Graaf) are the roughly spherical cell aggregations in the ovary containing an ovum and from which the egg is released during ovulation. ... // For ovary as part of plants see ovary (plants) An ovary is an egg-producing reproductive organ found in female organisms. ... Assisted reproductive technology (ART) is a general term referring to methods used to achieve pregnancy by artificial or partially artificial means. ...


Agents that enhance ovarian activity can be classified as either Gonadotropin releasing hormone, Estrogen antagonists or Gonadotropins. Gonadotropin Releasing Hormone (GnRH) is a peptide hormone responsible for the release of FSH and LH from the anterior pituitary. ... Estriol. ... For other uses, see Antagonist (disambiguation). ... Gonadotropins are protein hormones secreted by gonadotrope cells of the pituitary gland of vertebrates. ...

Contents

Gonadotropin releasing hormone

Either Gonadotropin releasing hormone (GnRH) itself or any of its agonist may be used. GnRH releases gonadotropins from the hypothalamus in the body. GnRH agonists includes i.e. Lupron. Gonadotropin-releasing hormone 1 (GNRH1 also called LHRH) is a peptide hormone responsible for the release of FSH and LH from the anterior pituitary. ... A GnRH agonist is a synthetic peptide that acts like the gonadotropin-releasing hormone (GnRH) but has a much longer biological half life. ...


Estrogen antagonists

Fertility medication inhibiting the effects of estrogen includes Clomiphene citrate and Aromatase inhibitors. Estriol. ... Categories: Stub | Selective estrogen receptor modulators ... Aromatase inhibitors (AI) are a class of drugs used in the treatment of breast cancer in post- menopausal women. ...


Clomiphene citrate

Main article: Clomiphene citrate

Clomiphene citrate is a SERM. It inhibits the negative feedback of estrogen and therefore stimulates ovulation. Categories: Stub | Selective estrogen receptor modulators ... Selective estrogen receptor modulators (SERMs) is a class of medication that acts on the estrogen receptor. ...


Aromatase inhibitors

Main article: Aromatase inhibitor

Although primarily a breast cancer treatment, aromatase inhibitors can also work as fertility medication, probably by a mechanism similar to clomiphene citrate. Aromatase inhibitors (AI) are a class of drugs used in the treatment of breast cancer in post- menopausal women. ...


Gonadotropins

Gonadotropins are the hormones in the body that normally stimulate the gonads (testes and ovaries). For medication, they can be extracted from urine or by genetic modification. Gonadotropins are protein hormones secreted by gonadotrope cells of the pituitary gland of vertebrates. ... A sex organ, or primary sexual characteristic, narrowly defined, is any of those parts of the body (which are not always bodily organs according to the strict definition) which are involved in sexual reproduction and constitute the reproductive system in an complex organism; namely: Male: penis (notably the glans penis...


Menotropins

Main article: Menotropins

Menotropins are urinary gonadotropins, i.e. they are extracted from the urine. Menotropin is an active substance for the treatment of fertility disturbances. ...


Recombinant gonadotropins

Recombinant gonadotropins are gonadotropins created by inserting the DNA coding it into bacteriae. The bacterial DNA is then called Recombinant DNA. Examples of recombinant FSH are Follistim and Gonal F, while Luveris is a recombinant LH. Recombinant DNA (rDNA) is an artificial DNA sequence resulting from the combination of different DNA sequences. ...


Human chorionic gonadotropin

Human chorionic gonadotropin (hCG) is normally produced during pregnancy. However, it can also replace LH as a fertility medication. Human chorionic gonadotropin (hCG) is a peptide hormone produced in pregnancy, that is made by the embryo soon after conception and later by the syncytiotrophoblast (part of the placenta). ...


Adverse effects

Estrogen antagonists and gonadotropins may stimulate multiple follicles and other ovarian hormones leading to multiple birth and possible ovarian hyperstimulation syndrome. Identical triplet brothers at graduation. ... Ovarian hyperstimulation syndrome (OHSS) is a complication from some forms of fertility medication. ...


See also

Manufacturers:

EMD Serono Ferring Pharmaceuticals is a pharmaceutical company that specializes on the development and marketing of peptides for the use in human medicine. ... Organon is a pharmaceutical company headquartered in Roseland, New Jersey that is part of Akzo Nobel. ...



 

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