Molecular structure of the flavone backbone (2-phenylchromen-4-one / 2-phenyl-1-benzopyran-4-one) Flavones are a class of flavonoids based on the backbone of 2-phenylchromen-4-one (2-phenyl-1-benzopyran-4-one) shown on the right. Flavonoids are a group of chemical compounds naturally found in certain fruits, vegetables, teas, wines, nuts, seeds, and roots. ...
Molecular structure of flavone The term flavonoid refers to a class of plant secondary metabolites based around a phenylbenzopyrone structure. ...
Natural flavones include Apigenin (4',5,7-trihydroxyflavone, Luteolin (3',4',5,7-tetrahydroxyflavone) and Tangeritin (4',5,6,7,8-pentamethoxyflavone). Synthetic flavones are Diosmin and Flavoxate Apigenin is a flavone that is the aglycone of apiin, isolated from parsley and celery, and apigetrin. ...
Luteolin Luteolin classified as a bioflavonel, and is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an agent in the prevention of inflammation, a promoter of carbohydrate metabolism, and an immune system modulator. ...
Tangeritin is a polymethoxylated flavone that is found in tangerine and other citrus peels. ...
Flavoxate is an anticholinergic with antimuscarinic effects. ...
Organic chemistry
In organic chemistry several methods exist for the synthesis of flavones: Organic chemistry is a specific discipline within chemistry which involves the scientific study of the structure, properties, composition, reactions, and preparation (by synthesis or by other means) of chemical compounds consisting of primarily carbon and hydrogen, which may contain any number of other elements, including nitrogen, oxygen, halogens as well...
- the Allan-Robinson reaction
- the Auwers synthesis
- the Baker-Venkataraman rearrangement
- the Algar-Flynn-Oyamada reaction
Another method is the dehydrative cyclization of certain 1,3-diaryl diketones [1] The Auwers synthesis in organic chemistry is a classic organic synthesis of a flavonol first reported by K. Auwers in 1908 [1]. The first step in this procedure is a acid catalized aldol condensation between benzaldehyde and a 3-oxypentanone to a o-hydroxychalcone. ...
The Baker-Venkataraman rearrangement is the chemical reaction of 2-acetoxyacetophenones with base to form 1,3-diketones. ...
The Algar-Flynn-Oyamada reaction is a chemical reaction whereby a chalcone undergoes an oxidative cyclization to form a flavonol. ...
this particular study making use of an ionic liquid solvent and microwave irradiation. Ionic liquid An ionic liquid is a liquid that contains essentially only ions. ...
Microwave chemistry is the science of applying microwave irradiation to chemical reactions . Microwaves act as high frequency electric fields and will generally heat anything with a mobile electric charge. ...
Wessely-Moser rearrangement The Wessely-Moser rearrangement (1930) [2] has been an important tool in structure elucidation of flavonoids. It involves the conversion of 5,7,8-trimethoxyflavone into 5,6,7-trihydroxyflavone on hydrolysis of the methoxy groups to phenol groups. It also has synthetic potential for example[3]: In chemistry, the methoxy prefix indicates the function group consisting of the methyl group and oxygen. ...
Phenol, also known under an older name of carbolic acid, is a colourless crystalline solid with a typical sweet tarry odor. ...
 This rearrangement reaction takes place in several steps: A ring opening to the diketone, B bond rotation with formation of an favorable acetylacetone-like phenyl-ketone interaction and C hydrolysis of two methoxy groups and ring closure. A rearrangement reaction is a broad class of organic reactions where the carbon skeleton of a molecule is rearranged to give a structural isomer of the original molecule. ...
A diketone is a molecule containing two carbonyl groups. ...
R-phrases , S-phrases , , , Flash point 34 °C Autoignition temperature 340 °C Explosive limits 2. ...
External links Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. ...
References - ^ A facile synthesis of flavones using recyclable ionic liquid under microwave irradiation Swapnil R. Sarda, Mohsin Y. Pathan, Vijaykumar V. Paike, Pandurang R. Pachmase, Wamanrao N. Jadhav, and Rajendra P. Pawar ARKIVOC 2006 (xvi) 43-48 Link:
- ^ Wessely, F.; Moser, G. H. Monatsh. Chem. 1930, 56, 97.
- ^ A Convenient Extension of the Wessely±Moser Rearrangement for the Synthesis of Substituted Alkylamino¯avones as Neuroprotective Agents In Vitro Ronan Larget, Brian Lockhart, Pierre Renard and Martine Largeron Bioorganic & Medicinal Chemistry Letters 10 (2000) 835±838
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