Also recognized as the forebrain, the prosencephalon gives rise to the diencephalon and the telencephalon. The prosencephalon emerges from the top, or front end of the neural tube, and is the most rostral of the three vesicles.
Profound development of prosencephalar areas in adult humans, especially the neopallium, creates the physiological basis for many of humans' unique skills related to memory, planning, conjecture and fabrication.
At 13.5 dpc, deficient growth of the mutant ventral forebrain is observed in the septum (Sep) and the medial ganglionic eminence (MGE) (cf.
The pattern of expression of Shh (b,d) and Nkx2.1 (f,h) at 11.5 dpc and that of Dlx1 (j,l) or of Pax6 (n,p) at 13.5 dpc are apparently not modified in homozygous mutants, suggesting that the patterning of the forebrain is not affected by the Vax1 mutation.
Cooperation of BMP7 and SHH in the induction of forebrain ventral midline cells by prechordal mesoderm.
Feeds |
Contact