A progressive rock / metal band led by Henning Pauly. The first album, Unweaving the Rainbow is a concept album based on the work of Richard Dawkins, a neo-Darwinist writer and features Dream Theater vocalist James LaBrie. The second concept album, An Absence of Empathy, features Sebastian Bach and other talented musicians. Clinton Richard Dawkins, FRS (born March 26, 1941), better known as Richard Dawkins, is a British zoologist, born in Nairobi, in Kenya. ... Dream Theater: (left to right) John Petrucci, Mike Portnoy, James LaBrie, Jordan Rudess and John Myung Dream Theater is an American progressive metal band formed by three students at the Berklee College of Music in the mid 1980s. ... Kevin James LaBrie (born May 5, 1963) is a Canadian vocalist who is best known as the lead singer in progressive metal band Dream Theater. ... Sebastian Bach (born April 3, 1968) was the lead vocalist of the 1980s heavy metal bands Madam X and Skid Row. ...
Discography
An Absence of Empathy (ProgRock Records, 2005)
Unweaving the Rainbow (ProgRock Records, 2003)
References and Links
FRAMESHIFT - Discography, MP3 and Reviews (http://www.progarchives.com/Progressive_rock_discography_BAND.asp?band_id=898)
Frameshift Official Homepage (http://www.frameshift2.com/)
However, the increased Na /Li countertransport is not a general characteristic of HS or band 3 deficiency, as it was not observed in patients 4 and 5, presenting band 3 and ankyrin deficiency, respectively.
The hypothesis that this band 3 mutation (band 3
Association with a nonsense mutation of the band 3 gene (Allele Lyon), and aggravation by a low-expression allele occurring in trans (Allele Genas).
A subset of patients with HS and spectrin deficiency have heterogeneous frameshift and nonsense mutations of the spectrin gene.
The disruption of this vertical association, via the weakening of one of its components which include spectrin-ankyrin, ankyrin-band 3, band 3-protein 4.2, and glycophorin C-protein 4.1, is proposed as the basis for the uncoupling of the membrane from its supportive skeleton, resulting in the shedding of membrane vesicles and surface area deficiency in HS.
Indeed, because the lateral mobility of band 3 is inversely related to the spectrin concentration, patients with spectrin deficiency may have hypermobile band 3, which could lead to an increased probability that areas of the lipid bilayer would become transiently depleted of band 3 and prone to shedding by exocytosis.
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