Please help improve this article or section by expanding it. Further information might be found on the talk page or at requests for expansion. This article has been tagged since January 2007.

Freebase refers to the standalone basic form of an alkaloid, as opposed to its water-soluble salt form. Most alkaloids are unstable and corrosive in their freebase form, and thus are usually stored in salt form, such as their hydrochloride salt. Image File history File links This is a lossless scalable vector image. ... The Metaweb is a website organised by sci-fi author Neal Stephenson. ... Acids and bases: Acid-base reaction pH Self-ionization of water Buffer solutions Systematic naming Acid-base extraction Acidity function Proton affinity Acids: Strong acids Weak acids Superacids Lewis acids Mineral acids Organic acids Bases: Strong bases Weak bases Superbases Lewis bases Organic bases edit In chemistry, a base is... Chemical structure of ephedrine, a phenethylamine alkaloid An alkaloid is, strictly speaking, a naturally occurring amine produced by a plant,[1] but amines produced by animals and fungi are also called alkaloids. ... For other uses, see Salt (disambiguation). ... In chemistry, hydrochlorides are salts resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic base (mostly amines). ...

When used as a verb, it refers to smoking freebase cocaine, crack cocaine, freebase heroin or more rarely freebase PCP. Freebasing also refers to the process of freeing the active ingredients of a drug from its adulterants with which, in the slang term, it has been "cut". Adulterants are various substances which are mixed into drugs as fillers by dealers, thus increasing the amount that they can sell. Adulterants commonly include inositol and baby powder in the case of cocaine, and a wide range of substances in the case of heroin. Cocaine is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. ... Cocaine is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. ... Heroin (INN: diacetylmorphine, BAN: diamorphine) is an opioid synthesized directly from the extracts of the opium poppy, Papaver somniferum. ... Phencyclidine (a contraction of the chemical name phenylcyclohexylpiperidine), abbreviated PCP, is a dissociative drug formerly used as an anesthetic agent, exhibiting hallucinogenic and neurotoxic effects. ... Inositol, (of which the most prominent naturally-ocurring form is myo-inositol, cis-1,2,3,5-trans-4,6-cyclohexanehexol), is a carbocyclic polyol that plays an important role as the structural basis for a number of secondary messengers in eukaryotic cells, including inositol phosphates, phosphatidylinositol (PI) and phosphatidylinositol...

Drugs smoked in their freebase form are generally more powerful, and act more rapidly, than their salts. This can make freebase drugs even more powerfully addictive than their salt equivalents. Some drugs such as methamphetamine, MDMA, mescaline and dimethyltryptamine are strong-smelling, corrosive oily yellow liquids when in base form and so are rarely ingested as bases, instead almost always being encountered as the hydrochloride or sulphate salts. This article is about the psychostimulant, d-methamphetamine. ... ecstasy and religious ecstasy MDMA, most commonly known today by the street name ecstasy, is a synthetic entactogen of the phenethylamine family whose primary effect is to stimulate the brain to rapidly secrete large amounts of serotonin, causing a general sense of openness, empathy, energy, euphoria, and well-being. ... This article does not cite any references or sources. ... Dimethyltryptamine (DMT), also known as N,N-dimethyltryptamine, is a psychedelic tryptamine. ...

Freebase heroin

Illegal heroin is sometimes distributed in its freebase form, highly adulterated with fillers. The users then add acid to convert it to its water-soluble salt form to make it injectable. This is typically done by mixing the freebase form of the drug with a commonly available mild acid such as acetic or citric acid, and warming the mixture in a spoon or aluminum foil in order to make an injectable solution. Oftentimes the solution is injected hot to add a rush as it is felt travelling through the user's body, although it is far less dangerous to let it cool to more of a warm state. Heroin (INN: diacetylmorphine, BAN: diamorphine) is an opioid synthesized directly from the extracts of the opium poppy, Papaver somniferum. ...

Freebase cocaine

As the name implies, "freebase" is the base form of cocaine, as opposed to the salt form of cocaine hydrochloride. Whereas cocaine hydrochloride is extremely soluble in water, cocaine base is insoluble in water and is therefore not suitable for drinking, snorting or injecting. Cocaine hydrochloride is not well-suited for smoking because the temperature at which it vaporizes is very high, and close to the temperature at which it burns; however, freebase cocaine base vaporizes at a low temperature, which makes it suitable for inhalation. Acids and bases: Acid-base reaction pH Self-ionization of water Buffer solutions Systematic naming Acid-base extraction Acidity function Proton affinity Acids: Strong acids Weak acids Superacids Lewis acids Mineral acids Organic acids Bases: Strong bases Weak bases Superbases Lewis bases Organic bases edit In chemistry, a base is... For other uses, see Salt (disambiguation). ... It has been suggested that this article or section be merged with Solution. ... Impact from a water drop causes an upward rebound jet surrounded by circular capillary waves. ... This article includes a list of works cited or a list of external links, but its sources remain unclear because it lacks in-text citations. ... This article or section is in need of attention from an expert on the subject. ... A combustion reaction taking place in a igniting match Combustion or burning is a complex sequence of exothermic chemical reactions between a fuel and an oxidant accompanied by the production of heat or both heat and light in the form of either a glow or flames. ...

Smoking freebase is preferred by many users because the cocaine is absorbed immediately into blood via the lungs, where it reaches the brain in about five seconds. The rush is much more intense than sniffing the same amount of cocaine nasally, but the effects do not last as long. The peak of the freebase rush is over almost as soon as the user exhales the vapor, but the high typically lasts 5–10 minutes afterwards. What makes freebase a particularly dangerous drug is that users typically don't wait that long for their next hit and will continue to smoke freebase until none is left. These effects are similar to those that can be achieved by injecting or "banging" cocaine hydrochloride, but without the risks associated with intravenous drug use (although there are other serious risks associated with smoking freebase). Human blood smear: a - erythrocytes; b - neutrophil; c - eosinophil; d - lymphocyte. ... The heart and lungs (from an older edition of Grays Anatomy) The lung is an organ belonging to the respiratory system and interfacing to the circulatory system of air-breathing vertebrates. ... Italic text // ahh addiing sum spiice iin hurr`` For other uses, see Brain (disambiguation). ... An intravenous drip in a hospital Intravenous therapy or IV therapy is the administration of liquid substances directly into a vein. ...

Freebase cocaine is produced by first dissolving cocaine hydrochloride in water. Once dissolved in water, cocaine hydrochloride (Coc HCl) dissociates into protonated cocaine ion (CocH⁺) and chloride ion (Cl^-). Any solids that remain in the solution are not cocaine (they are part of the cut) and are removed by filtering. A base, typically ammonia (NH₃) in the case of traditional "freebase" or sodium bicarbonate (baking soda) in the case of crack freebase, is added to the solution. Using ammonia as an example, the following net chemical reaction takes place: An electrostatic potential map of the nitrate ion (NO3−). Areas coloured red are lower in energy than areas colored yellow An ion is an atom or group of atoms which have lost or gained one or more electrons, making them negatively or positively charged. ... The chloride ion is formed when the element chlorine picks up one electron to form an anion (negatively-charged ion) Cl−. The salts of hydrochloric acid HCl contain chloride ions and can also be called chlorides. ... For other uses, see Solid (disambiguation). ... Dissolving table salt (NaCl) in water This article is about a chemical solution; for other uses of the term solution, see solution (disambiguation). ... In chemistry and common usage, a filter is a device (usually a membrane or layer) that is designed to block certain objects or substances while letting others through. ... Ammonia is a compound with the formula NH3. ... A pile of crack cocaine ‘rocks’. Crack cocaine is a form of cocaine. ... Vapours of hydrogen chloride in a beaker and ammonia in a test tube meet to form a cloud of a new substance, ammonium chloride A chemical reaction is a process that results in the interconversion of chemical substances. ...

NH₃ + CocH⁺ + Cl^- → NH₄Cl + Coc

As freebase cocaine (Coc) is insoluble in water, it precipitates and the solution becomes cloudy. To recover the freebase in the "traditional" manner, diethyl ether is added to the solution: Since freebase is highly soluble in ether, a vigorous shaking of the mixture results in the freebase being dissolved in the ether. As ether is practically insoluble in water, it can be siphoned off. The ether is then left to evaporate, leaving behind the nearly pure freebase. Alternatively, the freebase solution is simply evaporated until the freebase/cut solution "rocks up"—thereby producing the form commonly known as "crack" or "rock" cocaine. This article is about the chemical compound. ... Ether is the general name for a class of chemical compounds which contain an ether group — an oxygen atom connected to two (substituted) alkyl or aryl groups — of general formula R – O–R.[1] A typical example is the solvent and anesthetic diethyl ether, commonly referred to simply as ether... siphon principle A siphon (also spelled syphon) is a continuous tube that allows liquid to drain from a reservoir through an intermediate point that is higher than the reservoir, the up-slope flow being driven only by hydrostatic pressure without any need for pumping. ...

Since the manufacture of "traditional" freebase involves the use of flammable solvents, it is a dangerous process, particularly since it is often carried out outside a controlled laboratory environment without sufficient safety precautions.

The "traditional" procedure is dangerous because of the hazards of handling diethyl ether: it is extremely flammable, its vapors are heavier than air and can "creep" from an open bottle, and in the presence of oxygen it can form peroxides which can spontaneously combust. It is due both to these dangers and to the relative complexity of the "traditional" ammonia/ether method that the simpler "crack" method with sodium bicarbonate became the norm. Flammable or Flammability refers to the ease at which a substance will ignite, causing fire or combustion. ... Diethyl ether peroxides are a class of organic peroxides that slowly form in diethyl ether upon storage under air, light, or in the presence of metal by autoxidation. ...

Although freebase cocaine prepared with ammonia and ether is generally purer than freebase cocaine prepared with baking soda but no solvent, the cocaine fumes produced when the product is smoked are approximately equally pure, and the active ingredient ingested is exactly the same. Despite this, for many years "traditional" freebase smokers scorned "crack" freebase smokers—asserting incorrectly that these were fundamentally different drugs.

Freebase Methamphetamine

The most popular and effective method for use of methamphetamine is freebasing.

External links

Look up Freebase in
Wiktionary, the free dictionary.

• what does it mean when something is converted to a freebase?

• Cocaine-Drug of Illusion