Fructosamine, also known as Glycated Serum Protein (GSP) or Glycated Albumin, is used primarily to identify the plasma glucose concentration over time and so assess diabetic control . Blood plasma is the liquid component of blood, in which the blood cells are suspended. ... Glucose (Glc), a monosaccharide, is one of the most important carbohydrates. ... In chemistry, concentration is the measure of how much of a given substance there is mixed with another substance. ... This article is about the disease that features high blood sugar. ...

Indications

More commonly diabetics have their average control assessed with the Glycosylated hemoglobin measurement that indicates glucose levels over the preceeding 6 weeks; as reflected by the perminant glycosylation of a small fraction of the hemoglobin molecules in their blood. However this is not appropriate where there has been a recent change in diet or treatment within 6 weeks, nor if there are abnormalities of red blood cell aging process or mix of haemaglobin subtypes (predominantly HbA in normal adults). Hence people with recent blood loss or hemolytic anemia, or hemoglobinopathy such as sickle-cell disease are not suitable for Glycosylated hemaglobin test. The Fructosamine test is used instead in these circumstances and it similarly reflects an average of blood glucose levels, but over a shorter period of 2 to 3 weeks. Glycosylated Hemoglobin is used primarily to identify the plasma glucose concentration over time. ... 3-dimensional structure of hemoglobin. ... Hemolytic anemia is anemia due to hemolysis, the abnormal breakdown of red blood cells either in the blood vessels (intravascular hemolysis) or elsewhere in the body (extravascular). ... Hemoglobinopathy is a kind of genetic defect that results in abnormal structure of one of the globin chains of the hemoglobin molecule. ... Sickle-shaped red blood cells Sickle cell disease is a general term for a group of genetic disorders caused by sickle hemoglobin (Hgb S). ...

Interpretation of results

There is no standard reference range available for this test. The reference values depends upon the factors of patient age, gender, sample population and test method. Hence each laboratory reports will include their specific reference range for the test.

See also

• Diabetes mellitus