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Encyclopedia > Fucose
Fucose
(L-fucose)
Chemical name (3R,4R,5S,6S)-6-methyloxane-2,3,4,5-tetrol
Synonym for L-fucose 6-deoxy-L-galactose
Synonym for D-fucose 6-deoxy-D-galactose
Chemical formula C6H12O5
Molecular mass 164.16 g mol−1
Melting point 144°C
CAS number 17-10-6 (L-fucose)
(D-fucose)

Fucose is a hexose sugar with the chemical formula C6H12O5. It is found on N-linked glycans on the mammalian and plant cell surface. Alpha1→3 linked core fucose is a suspected carbohydrate antigen for IgE-mediated allergy. [1] Image File history File links Fucose_2a. ... IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... General Name, Symbol, Number carbon, C, 6 Chemical series nonmetals Group, Period, Block 14, 2, p Appearance black (graphite) colorless (diamond) Atomic mass 12. ... General Name, Symbol, Number hydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1, 1, s Appearance colorless Atomic mass 1. ... General Name, Symbol, Number oxygen, O, 8 Chemical series Nonmetals Group, Period, Block 16, 2, p Appearance colorless Atomic mass 15. ... The molecular mass (abbreviated MM) of a substance, called molecular weight and abbreviated as MW, is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... The melting point of a solid is the temperature at which it changes state from solid to liquid. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... Image File history File links Download high resolution version (1115x1948, 7 KB) Summary Chemical structure of fucose. ... A hexose is a monosaccharide with six carbon atoms. ... Magnified view of refined sugar crystals. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... Polysaccharides (sometimes called glycans) are relatively complex carbohydrates. ... A cell is a single unit or compartment, enclosed by a border or wall. ... Carbohydrates are chemical compounds that contain oxygen, hydrogen, and carbon atoms. ... An antigen is a molecule that stimulates the production of antibodies. ... An allergy or Type I hypersensitivity is an immune system malfunction whereby a persons body is hypersensitised to react immunologically to typically nonimmunogenic substances. ...


Two structural features distinguish fucose from other six-carbon sugars present in mammals: the lack of a hydroxyl group on the carbon at the 6-position (C-6) and the L-configuration. Hydroxyl group The term hydroxyl group is used to describe the functional group -OH when it is a substituent in an organic compound. ...


In the fucose-containing glycan structures, fucosylated glycans, fucose can exists as a terminal modification or serve as an attachment point for adding other sugars [2].


References

1. Image:Free_review.png Fucose: biosynthesis and biological function in mammals. 2003 Jul; PMID 12651883 Free text
2. Image:Free_text.png The O-linked fucose glycosylation pathway: identification and characterization of a uridine diphosphoglucose: fucose-beta1,3-glucosyltransferase activity from Chinese hamster ovary cells. 1999 Jul; PMID 10362837 Free text
3. PubChem Image File history File links Free_review. ... See Wikipedia:PMID for the usage of PMID in Wikipedia. ... Image File history File links Free_text. ... See Wikipedia:PMID for the usage of PMID in Wikipedia. ...


  Results from FactBites:
 
Why Fucose? (825 words)
Fucose is a rare sugar, one of the eight known bioactive sugars essential for proper cell to cell communication.
Fucose is also excreted in breast milk and may play a part in the transfer of immunity to the newborn.
Fucose is a rare sugar not commonly consumed in most people's diets, at least not to a level that is beneficial to the body.
  More results at FactBites »

 

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