After dropping out of the Russian language department at the Tokyo School of Foreign Languages (東京外国語学校), Futabatei published the literary criticism Shōsetsu Sōron at the encouragement of the critic and author Tsubouchi Shōyō in 1886. Futabatei's first novel Ukigumo was never finished, but its realist style strongly influenced fellow authors in his day. Futabatei was accomplished in Russian and translated the work of Ivan Turgenev and other Russian realists into Japanese.
Futabatei died of tuberculosis on the Bay of Bengal while returning from Russia as a special correspondent for the Asahi Shimbun newspaper. He was cremated and buried in Singapore.
The origin of his pen name is in the curse his father said when told by his son that he aspired to study literature: Kutabatte shimee (くたばってしめぇ), "Drop dead!"
Shimei is a person who was referenced in the Hebrew Bible and Rabbinical literature.
Shimei afterward became Solomon's instructor, and restrained him from marrying the daughter of Pharaoh, so that she did not become the wife of the King of Israel until after his teacher's death (Midr.
The family of the Shimeites, as a branch of the tribe of Levi, is mentioned in Numbers 3:18, 21; I Chronicles 23:7, 10, 11 ("Shimei" in verse 9 is evidently a scribal error); and in Zechariah 12:13.