- is the name of a group of biochemical compounds responsible for the activation of GTP-binding proteins' GTPase function across a wide range of organisms, thus inactivating the protein.
These tags can direct one protein to the cell's nucleus, where it regulates gene expression, say, while another is sent to the hinterlands of the cell membrane, where it receives environmental signals.
Protein targeting is crucial even as cells are building proteins—otherwise, for example, proteins won't fold into the proper shape.
During this process, two GTPases, one in SRP and one in the SRP receptor (named Ffh and FtsY in bacteria, respectively), form a complex in which both proteins reciprocally activate the GTPase reaction of one another.