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The town stands on the Mersey, and on the Warrington, Garston, and Liverpool railway, 6 miles SE of Liverpool; was once noted for extensive salt-works; is now a sub-port to Liverpool, with new docks; and has a railway station with telegraph, and a post office under Liverpool.
In 1835 Garston was a township in the parish of Childwall.
For probate purposes prior to 1858, Garston was in the Archdeaconry of Chester, in the Diocese of Chester.
Garston is the premier short-sea shipping port for north-west England, serving the hinterland of Merseyside, Lancashire, Cheshire and the north and west Midlands.
The most inland port on the River Mersey, Garston is within 10 km of Liverpool city centre, yet only seven miles from the national motorway network via dual lane trunk roads.
Garston is situated directly adjacent to the A561, which links via the A562 and A5300 to the M56, M57 and M62, and the national motorway network.