Gascozark, Missouri is an unincorporated community on Missouri Supplemental Route AB (formerly U.S. Highway 66) in western Pulaski County. The origin of the town's name is a combination of the Gasconade River west of the location and Ozarks, the surrounding area. Numerous homes are located here along with a couple of old stores. Missouri Supplental Routes are officially designated as State Secondary Roads. They are roads within the state of Missouri designated with letters. ... U.S. Highway 66 or Route 66 was a highway in the U.S. Highway system. ... Pulaski County is a county located in the U.S. state of Missouri. ... The Gasconade River is a tributary of the Missouri River, about 265 mi (425 km) long[1], in south-central and central Missouri in the United States. ... Ozark redirects here. ...