FACTOID # 87: 22% of American women aged 20 gave birth while in their teens. In Switzerland and Japan, only 2% did so.
 
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Encyclopedia > Genetic interactions

Genetic interactions, in genetics, are interactions that occur between two or more mutations that results in a new phenotype. Studying genetic interactions can reveal gene function, the nature of the mutations, functional redundancy, and protein interactions. Because protein complexes are responsible for most biological functions, genetic interactions are a powerful tool.


Examples of pair-wise interactions:

  • Suppression - the double mutant is wild type
  • Epistasis - the double mutant is like one of the single mutants
  • Synthetic lethality - the double mutant is lethal
  • Intragenic complementation - two mutations cause similar phenotypes and map to the same locus yet show complementation in heterozygotes.
  • Unlinked non-complementation - two mutations fail to complement but do not map to the same locus

  Results from FactBites:
 
Genetics - Wikipedia, the free encyclopedia (2007 words)
Genetics (from the Greek genno γεννώ= give birth) is the science of genes, heredity, and the variation of organisms.
The word "genetics" was first suggested to describe the study of inheritance and the science of variation by the prominent British scientist William Bateson in a personal letter to Adam Sedgwick, dated April 18, 1905.
The foundational discipline is population genetics which studies the distribution of and change in allele frequencies of genes under the influence of the four evolutionary forces: natural selection, genetic drift, mutation and migration.
Genetic Interactions Between the RhoA and Stubble-stubbloid Loci Suggest a Role for a Type II Transmembrane Serine ... (6595 words)
Genetic Interactions Between the RhoA and Stubble-stubbloid Loci Suggest a Role for a Type II Transmembrane Serine Protease in Intracellular Signaling During Drosophila Imaginal Disc Morphogenesis -- Bayer et al.
Sb-sbd mutations interact genetically with mutant alleles of
, A., and J., 1988  Interaction of the Stubble-stubbloid locus and the Broad-Complex of Drosophila melanogaster.
  More results at FactBites »


 

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