Gilbert syndrome the most common hereditary cause of increased unconjugated bilirubin. Its main effect is cosmetic (jaundice) and does not require treatment. In medicine, the term syndrome is the association of several clinically recognizable features, signs, symptoms, phenomena or characteristics which often occur together, so that the presence of one feature alerts the physician to the presence of the others. ... For the scientific journal Heredity see Heredity (journal) Heredity (the adjective is hereditary) is the transfer of characters from parent to offspring, either through their genes or through the social institution called inheritance (for example, a title of nobility is passed from individual to individual according to relevant customs and... Bilirubin is a yellow breakdown product of haem (heme in American English) catabolism. ... Jaundice, also known as icterus (adjective:Icteric), is yellowing of the skin, sclera (the white of the eyes) and mucous membranes caused by increased levels of bilirubin in the human body. ...
Crigler-Najjar syndrome is a disorder of bilirubin metabolism. ... Dubin-Johnson syndrome is an autosomal recessive disease which presents shortly after birth with an increase of conjugated bilirubin without elevation of liver enzymes (ALT, AST). ...
Gilbert'ssyndrome is a common inherited disorder that affects the processing by the liver of the pigments in the bile called bilirubin.
Gilbert'ssyndrome is most often recognised in the second or third decade of life and is rarely diagnosed before puberty.
At least 30% of patients with Gilbert'ssyndrome are asymptomatic, apart from the presence of mild jaundice, and are unaware of the abnormality until it is detected by incidental laboratory examination or in the course of family studies.