Glipizide is an oral medium-to-long acting anti-diabetic drug from the sulfonylurea class. http://kimoruni. ... Sulfonylurea derivatives are a class of antidiabetic drugs that are used in the management of diabetes mellitus type 2 (adult-onset). They act by increasing insulin release from the beta cells in the pancreas. ...
It is available under the brand name Glucotrol by Pfizer, originally available in 1984. Pfizer sells Glucotrol in doses of 5 and 10 milligrams and Glucotrol XL (an extended release form of glipizide) in doses of 2.5, 5, and 10 milligrams. Other companies sell generic forms of glipizide, most commonly extended release tablets of 5 and 10 milligrams. Pfizer, Incorporated (NYSE: PFE), is a global pharmaceutical company, with headquarters in New York City. ...
Glipizide is used to treat type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood), particularly in people whose diabetes cannot be controlled by diet alone.
Glipizide lowers blood sugar by stimulating the pancreas to secrete insulin and helping the body use insulin efficiently.
Glipizide is not used to treat type 1 diabetes (condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood).
Glipizide is an oral blood-glucose-lowering drug of the sulfonylurea class.
Glipizide is a whitish, odorless powder with a pKa of 5.9.
As water from the gastrointestinal tract enters the tablet pressure increases in the osmotic layer and "pushes" against the drug layer, resulting in the release of through a small, laser-drilled orifice in the membrane on the drug side of the tablet.