A glomus tumor is a rare neoplasm usually found in the skin of the extremities. It arises from the glomus body. They are usually solitary and small, and most often are found under the fingernails. They are often painful, and the pain is reproduced when the lesion is placed in cold water. Neoplasia (literally: new growth) is sudden and abnormal growth in a tissue or organ. ...
References
Glomus tumor in Wheeless's Textbook of Orthopedics (http://www.wheelessonline.com/o6/169.htm)
The normal glomus unit is a neuromyoarterial apparatus that functions to regulate skin circulation and is found subungually, on the finger tip pulp, on the base of the foot and the rest of body in descending order.
Clinically, glomustumors are characterized by a triad of sensitivity to cold, localized tenderness and severe intermittent pain.
Under the microscope, glomustumors are found at the dermal and subdermal junction and have a fibrous capsule.
Unlike conventional glomustumors, which consist of small polygonal cells with dark round nuclei and scanty cytoplasm, the epithelioid lesions are composed of large polygonal to spindle-shaped cells with abundant eosinophilic cytoplasm and large, irregularly shaped nuclei.
Infiltrative glomustumor arising from a benign glomustumor: a distinctive immunohistochemical pattern in the infiltrative component.
Glomustumor of the stomach: cytologic diagnosis by endoscopic ultrasound-guided fine-needle aspiration.
Feeds |
Contact