Glutamate dehydrogenase is an enzyme, present in mitochondria, as are some of the other enzymes required for urea synthesis, that converts glutamate to α-Ketoglutarate, and vice versa. Its cofactor for the glutamate to α-Ketoglutarate reaction, which produces ammonium as well, is NAD+. Its cofactor for the reverse reaction, α-Ketoglutarate to glutamate, is NADP+. This reverse reaction uses ammonium to incorporate nitrogen into glutamate. Ribbon diagram of the catalytically perfect enzyme TIM. Factor D enzyme crystal prevents the immune system from inappropriately running out of control. ... In cell biology, a mitochondrion is an organelle found in the cells of most eukaryotes. ... Glutamate is the anion of glutamic acid. ... Ketoglutaric acid is used for either of two crystalline keto derivatives C5H6O5 of glutaric acid. ... A cofactor is the following: In mathematics a cofactor is the minor of an element of a square matrix. ... Fumes from hydrochloric acid and ammonia forming a white cloud of ammonium chloride The Ammonium cation is a positively charged polyatomic ion of the chemical formula NH4+ and a molecular mass of 18. ... Nicotinamide adenine dinucleotide (NAD+) (Note that the adenonosyl sugar is of the wrong absolute configuration in the diagram: it should have the same configuration as the nicotinamide sugar. ... Nicotinamide adenine dinucleotide (NAD+) Nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP) are two important coenzymes found in cells. ... General Name, Symbol, Number nitrogen, N, 7 Chemical series nonmetals Group, Period, Block 15, 2, p Appearance colorless Atomic mass 14. ...
Glutamatedehydrogenase is an enzyme, present in mitochondria of eukaryotes, as are some of the other enzymes required for urea synthesis, that converts glutamate to α-Ketoglutarate, and vice versa.
Glutamic acid (Glu), also referred to as glutamate (the anion), is one of the 20 proteinogenic amino acids.
Glutamic acid is present in a wide variety of foods and is responsible for one of the five basic tastes of the human sense of taste (umami), especially in its physiological form, the sodium salt of glutamate in a neutral pH.
Glutamate easily passes the blood brain barrier: "glutamate flux from plasma into brain is mediated by a high affinity transport system at the BBB" [1].
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