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The Gluten exorphines are a group of opioidpeptides which are formed during digestion of the gluten protein. They are usually broken down into amino acids by digestion enzymes, but in some individuals they are not. They are then accumulated in the body over time and can lead to a peptide poisoning. This is particularly often reported in patients with ADHD, autism and schizophrenia. Gluten exorphines mimick the effects of opiates and therefore influence the mind. This is partly the basis for the Gluten-free, casein-free diet. Withdrawal symptoms are reported in severe cases. The term opiate refers to the alkaloids found in opium, an extract from the seed pods of the opium poppy (). It has also traditionally referred to natural and semi-synthetic derivatives of morphine. ... Peptides (from the Greek πεπτος, digestable), are the family of molecules formed from the linking, in a defined order, of various amino acids. ... Wheat - a prime source of gluten Gluten is an amorphous ergastic protein found combined with starch in the endosperm of some cereals, notably wheat, rye, and barley. ... In chemistry, an amino acid is any molecule that contains both amino and carboxylic acid functional groups. ... Ribbon diagram of the catalytically perfect enzyme TIM. Factor D enzyme crystal prevents the immune system from inappropriately running out of control. ... DISCLAIMER Please remember that Wikipedia is offered for informational use only. ... Autism is classified as a neurodevelopmental disorder that manifests itself in markedly abnormal social interaction, communication ability, patterns of interests, and patterns of behavior. ... Many parents of children with autism have reported that a gluten-free casein-free diet helps their children. ...
There are 5 known gluten exorphines with known structure:
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