A HACEK organism is one of a set of slow-growing Gram negativebacteria that form a normal part of the human flora. They are a frequent cause of inflammation of the inner layer of the heart, (endocarditis) in children.
The name is formed from their initials:
Haemophilus aphrophilus and Haemophilus paraphrophilus
A hacek or háček ("ˇ", pronounced HUH-check), also known as a caron, is a diacritic placed over certain letters to indicate palatalization or jotation in the orthography of some Slavic and Baltic languages.
The use of hacek (and the acute) for Latin characters was introduced by Jan Hus in the 15th century into the Czech language and today it is also used by the Slovaks, Slovenians, Croatians, Upper Lusatian and Lower Lusatian Sorbs, Lithuanians, Latvians and partly by the Poles.
As the valves of the heart do not actually receive any blood supply of their own, which may be surprising given their location, defense mechanisms (such as white blood cells) cannot enter.
HACEKorganisms are a group of bacteria that live on the dental gums, and are associated with IV drug users who contaminate their needles with saliva.
High dose antibiotics are administered by the intravenous route to maximize diffusion of antibiotic molecules into vegetation(s) from the blood filling the chambers of the heart.