Rev. Harold Lloyd Henderson (1907-1993) was a Presbyterian minister who was mayor of Portage la Prairie, Manitoba from 1947 to 1966 and again from 1971 to 1974. Henderson ran as a candidate at the Liberal leadership conventions of 1958 and 1968, receiving one vote in his first attempt (on that occasion he was also a Liberal delegate) and none in his second.

Henderson also ran for the leadership of the Manitoba Liberal Party on three occasions. He received 27 votes in 1961, finishing fourth out of four candidates. He fell to 16 votes in 1969, again finishing fourth out of four. In 1975 he was the only opponent of Charles Huband, losing by 381 votes to 87.

In the 1958 Canadian election, Henderson was a Liberal candidate in the riding of Portage-Neepawa placing a distant second. He also ran as an independent candidate in the same riding in the 1962 and 1963 elections placing last each time. Somewhat curiously, he never sought election to the provincial legislature.