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Encyclopedia > Histiocytosis
Malignant histiocytosis
ICD-10 C96.1
ICD-9 202.3

Though histiocytosis can refer to any of several specific diseases, the term is generally used to refer to a rare blood disease that is caused by an excess of white blood cells called histiocytes. The histiocytes cluster together and can attack the skin, bones, lung, liver, spleen, gums, ears, eyes, and/or the central nervous system. The disease can range from limited involvement that spontaneously regresses to progressive multiorgan involvement that can be chronic and debilitating. In some cases, the disease can be life-threatening. The following codes are used with International Statistical Classification of Diseases and Related Health Problems. ... // C00-D48 - Neoplasms (C00-C14) Malignant neoplasms, lip, oral cavity and pharynx (C00) Malignant neoplasm of lip (C01) Malignant neoplasm of base of tongue (C02) Malignant neoplasm of other and unspecified parts of tongue (C03) Malignant neoplasm of gum (C04) Malignant neoplasm of floor of mouth (C05) Malignant neoplasm of... The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ... A Histiocyte is a cell that is part of the human immune system. ... For alternate meanings see skin (disambiguation). ... A miserable stubborn cantankerous old mans, whos actually quite good humoured & an enjoyable compadre to play online alongside if you catch him on a good day. ... The lungs flank the heart and great vessels in the chest cavity. ... The liver is the largest internal organ of the human body. ... The spleen is a ductless, vertebrate gland that is not necessary for life but is closely associated with the circulatory system, where it functions in the destruction of old red blood cells in holding a reservoir of blood. ... The gingiva, or gums, consist of the tissue surrounding the roots of the teeth and covering the jawbone. ... For an alternative meaning, see ear (botany). ... This article refers to the sight organ. ... A diagram showing the CNS: 1. ...


In some ways, histiocytosis is similar to cancer and has historically been treated by oncologists with chemotherapy and radiation. Unlike cancer, histiocytosis sometimes goes into remission without treatment. When normal cells are damaged beyond repair, they are eliminated by apoptosis. ... Oncology is the medical subspecialty dealing with the study and treatment of cancer. ... Chemotherapy is the use of chemical substances to treat disease. ... Radiation in Physics is the process of emitting energy in the form of waves or particles. ...


The vast majority of people diagnosed with histiocytosis are children under the age of 10, but it is also found in adults of all ages.


It is estimated that histiocytosis affects 1 in 200,000 children born each year in the United States. This illness is so rare, there is little research into its cause and treatment, and it is often referred to as an orphan disease, meaning it strikes too few people to generate government-supported research and that no particular medical specialisms "own" the disease and no large organisations are providing support. A rare disease has such a low prevalence in a population that a doctor in a busy general practice would not expect to see more than one case a year. ...


Patients and families can gain some support by contacting patient organisations such as the Histiocytosis Association of America ([1]) or the Histiocytosis Research Trust ([2]).


The Histiocytosis Association of America has several stable and proven treatment protocols available only for physicians ([3]).


Another histiocytic disorder is HLH (hemophagocytic lymphohistiocytosis), where there is an excess of both histiocytes and lymphocytes. This disease can be hereditary. Other histiocytic disorders include malignant histiocytosis and sinus histiocytosis. Though Histiocytosis can refer to any of several specific diseases, the term is generally used to refer to a rare blood disease that is caused by an excess of white blood cells called histiocytes. ... A lymphocyte is a type of white blood cell involved in the human bodys immune system. ... Malignant histiocytosis is a hereditary disease found in the Bernese Mountain Dog characterized by histiocytic infiltration of the lungs and lymph nodes. ...


Histiocytosis is frequently associated with diabetes insipidus, even after several years of diagnosis and successful therapy. Diabetes insipidus (DI) is a disease characterized by excretion of large amounts of severely diluted urine, which cannot be reduced when fluid intake is reduced. ...

Contents


Alternative Names

Pulmonary Histiocytosis X, Histiocytosis X, Eosinophilic Granuloma, Nonlipid Reticuloendotheliosis, Langerhans cell histiocytosis, Letterer-Siwe Disease, Hand-Schuller-Christian Disease, Pulmonary Langerhans Granulomatosis, LCH. This article or section is in need of attention from an expert on the subject. ...


Common treatments

Please add more in alphabetical order. Cladribine is a drug used to treat hairy cell leukemia (leukemic reticuloendotheliosis). ... Cladribine is a drug used to treat hairy cell leukemia (leukemic reticuloendotheliosis). ... Cladribine is a drug used to treat hairy cell leukemia (leukemic reticuloendotheliosis). ... Etoposide: chemical structure Etoposide phosphate (Eposin®, Etopophos®, Vepesid®, VP-16®) is an inhibitor of the enzyme topoisomerase II. It is used as a form of chemotherapy for malignancies such as lung cancer, testicular cancer, lymphoma, non-lymphocytic leukemia, and glioblastoma multiforme. ... Vinblastine is a drug used to treat certain kinds of cancer, including Hodgkins lymphoma, non-small cell lung cancer and breast cancer or testicular cancer. ... Vinblastine is a drug used to treat certain kinds of cancer, including Hodgkins lymphoma, non-small cell lung cancer and breast cancer or testicular cancer. ...


See also

Malignant histiocytosis is a hereditary disease found in the Bernese Mountain Dog characterized by histiocytic infiltration of the lungs and lymph nodes. ... The Bernese Mountain Dog (also called Berner Sennenhund or Bouvier Bernois) is a versatile cattle-herding or farm dog originating in the canton of Berne in Switzerland. ...

External links


  Results from FactBites:
 
Histiocytosis - Wikipedia, the free encyclopedia (348 words)
Though histiocytosis can refer to any of several specific diseases, the term is generally used to refer to a rare blood disease that is caused by an excess of white blood cells called histiocytes.
It is estimated that histiocytosis affects 1 in 200,000 children born each year in the United States.
Histiocytosis is frequently associated with diabetes insipidus, even after several years of diagnosis and successful therapy.
Histiocytosis (522 words)
Histiocytosis is the most prevalent cancer in Bernese Mountain Dogs and is a common cause of early death.
Histiocytosis is a cancer in which histiocytes proliferate rapidly and invade a wide variety of tissues.
Histiocytosis is quite rare in other breeds with the exception of Flat Coated Retrievers, but it is the most common cancer in Bernese Mountain Dogs comprising 25% of all cases.
  More results at FactBites »


 

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