Howard Martin Temin (December 10, 1934 – February 9, 1994) was a U.S. geneticist.
The discovery of reverse transcriptase is one of the most important of the modern era of medicine, as reverse transcriptase is the central enzyme in several widespread human diseases, such as HIV, the virus that causes AIDS, and Hepatitis B.
Born in Philadelphia, Pennsylvania, a long-time advocate against smoking, Temin died at the age of 59 from lung cancer, although he himself was never a smoker.
HowardM. Temin, a cancer researcher, who won the Nobel Prize for discovering an enzyme, reverse transcriptase, that overturned a central tenet of molecular biology, died of lung cancer Wednesday, at his home in Madison, Wis. He was 59.
Howard Martin Temin was born in Philadelphia in 1934.
Temin was puzzled why RNA viruses were an exception to the central dogma, and suggested in 1964, that some animal viruses may harbor reverse transcriptase, which would permit duplication of the virus's RNA into DNA for better biological adjustment after the virus entered a DNA-dominated animal cell.
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