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Hydrolase - Wikipedia, the free encyclopedia (153 words) |
 | In biochemistry, a hydrolase is an enzyme that catalyzes the hydrolysis of a chemical bond. |
| Systematic names of hydrolases are formed as "substrate hydrolase." However, common names are common, using only "substratease." For example, a nuclease is a hydrolase that cleaves nucleic acids. |
| Hydrolases are classified as EC 3 in the EC number classification of enzymes. |
| FAAH - Fatty-acid amide hydrolase (5532 words) |
| The enzyme fatty acid amide hydrolase (FAAH) catalyses hydrolysis of oleamide, a sleep-inducing lipid whose concentration in the cerebrospinal fluid (CSF) is elevated in sleep-deprived mammals. |
| The distribution in the rat brain of fatty acid amide hydrolase (FAAH) an enzyme that catalyzes the hydrolysis of the endogenous cannabinoid anandamide was studied by immunohistochemistry. |
| Moreover, we observed a decreased activity of the anandamide membrane transporter (AMT) and of the anandamide hydrolase [ fatty acid amide hydrolase (FAAH)], whereas the binding of anandamide to cannabinoid receptors was unaffected. |
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