Structure of hydroxyproline

4-Hydroxyproline, or hydroxyproline (C₅H₉O₃N), is an uncommon amino acid, abbreviated as HYP, e.g., in Protein Data Bank. Its IUPAC name is 4-hydroxypyrrolidine-2-carboxylic acid. Hydroxyproline differs from proline by the presence of a hydroxyl (OH) group attached to the C (gamma) atom. Other hydroxyprolines also exist in nature, notably 2,3-cis 3,4-trans-dihydroxyproline, which occurs in diatom cell walls, and is postulated to have a role in silica deposition. In science, a common name is any name by which a species or other concept is known that is not the official scientific name. ... IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... Image File history File links Hydroxyproline. ... Image File history File links Hydroxyproline. ... General Name, Symbol, Number carbon, C, 6 Chemical series nonmetals Group, Period, Block 14, 2, p Appearance black (graphite) colorless (diamond) Atomic mass 12. ... General Name, Symbol, Number hydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1, 1, s Appearance colorless Atomic mass 1. ... General Name, Symbol, Number oxygen, O, 8 Chemical series Nonmetals, chalcogens Group, Period, Block 16, 2, p Appearance colorless Atomic mass 15. ... General Name, Symbol, Number nitrogen, N, 7 Chemical series nonmetals Group, Period, Block 15, 2, p Appearance colorless Atomic mass 14. ... An amino acid residue is what is left of an amino acid once a molecule of water has been lost (an H+ from the nitrogenous side and an OH- from the carboxylic side) in the formation of a peptide bond. ... The Protein Data Bank (PDB) is a repository for 3-D structural data of proteins and nucleic acids. ... Diatoms (Gr. ... A cell wall is a more or less solid layer surrounding a cell. ... The chemical compound silicon dioxide, also known as silica, is the oxide of silicon, chemical formula SiO2. ...

Hydroxyproline is produced by hydroxylation of the amino acid proline. It is not coded for by DNA, however, and is hydroxylated after protein synthesis. Along with proline, it is one of two cyclic amino acids found in proteins. Hydroxylation is any chemical process that introduces one or more hydroxyl groups (-OH) into a compound (or radical) thereby oxidising it. ... L-Proline is one of the twenty proteinogenic units which are used in living organisms as the building blocks of proteins. ... The general structure of a section of DNA Deoxyribonucleic acid (DNA) is a nucleic acid —usually in the form of a double helix— that contains the genetic instructions specifying the biological development of all cellular forms of life, and most viruses. ... An overview of protein synthesis. ...

Hydroxyproline is a major component of the protein collagen. It helps provide stability to the triple-helical structure of collagen by forming hydrogen bonds. Hydroxyproline is found in few proteins other than collagen. A representation of the 3D structure of myoglobin, showing coloured alpha helices. ... Tropocollagen triple helix. ... Protein folding is the process by which a protein structure assumes its functional shape or conformation. ... Snapshot from a simulation of liquid water. ...

Proline hydroxylation requires ascorbic acid. Most effects of absence of ascorbic acid in humans come from the resulting defect in hydroxylation of proline residues of collagen, with reduced stability of the collagen molecule causing scurvy. L-Proline is one of the twenty proteinogenic units which are used in living organisms as the building blocks of proteins. ... This article deals with the molecular aspects of ascorbic acid. ... This article deals with the molecular aspects of ascorbic acid. ... Hydroxylation is any chemical process that introduces one or more hydroxyl groups (-OH) into a compound (or radical) thereby oxidising it. ... L-Proline is one of the twenty proteinogenic units which are used in living organisms as the building blocks of proteins. ... Tropocollagen triple helix. ... The word stability has a number of technical meanings, all related to the common meaning of the word. ... Scurvy (N.Lat. ...