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Encyclopedia > Hypernatremia
Hypernatremia
Classifications and external resources
ICD-10 E87.0
ICD-9 276.0
DiseasesDB 6266
eMedicine emerg/263 

Hypernatremia is an electrolyte disturbance consisting of an elevated sodium level in the blood (compare to hyponatremia, meaning a low sodium level). The most common cause of hypernatremia is not an excess of sodium, but a relative deficit of free water in the body. For this reason, hypernatremia is often synonymous with the less precise term dehydration. The International Statistical Classification of Diseases and Related Health Problems (commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The following codes are used with International Statistical Classification of Diseases and Related Health Problems. ... // E00-E35 - Endocrine diseases (E00-E07) Disorders of thyroid gland (E00) Congenital iodine-deficiency syndrome (E01) Iodine-deficiency-related thyroid disorders and allied conditions (E02) Subclinical iodine-deficiency hypothyroidism (E03) Other hypothyroidism (E030) Congenital hypothyroidism with diffuse goitre (E031) Congenital hypothyroidism without goitre (E032) Hypothyroidism due to medicaments and other... The International Statistical Classification of Diseases and Related Health Problems (commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ... The Diseases Database is a free website that provides information about the relationships between medical conditions, symptoms, and medications. ... eMedicine is an online clinical medical knowledge base that was founded in 1996. ... Electrolyte disturbance refers to an abnormal change in the levels of electrolytes in the body. ... General Name, Symbol, Number sodium, Na, 11 Chemical series alkali metals Group, Period, Block 1, 3, s Appearance silvery white Atomic mass 22. ... The electrolyte disturbance hyponatremia or hyponatraemia exists in humans when the sodium level in the plasma falls below 135 mmol/l. ... Water is a chemical substance that is essential to all known forms of life. ... Dehydration (hypohydration) is the removal of water (hydro in ancient Greek) from an object. ...


Water is lost from the body in a variety of ways, including perspiration, insensible losses from breathing, and in the feces and urine. If the amount of water ingested consistently falls below the amount of water lost, the serum sodium level will begin to rise, leading to hypernatremia. Rarely, hypernatremia can result from massive salt ingestion, such as may occur from drinking seawater. Sweating (also called perspiration or sometimes transpiration) is the loss of a watery fluid, consisting mainly of sodium chloride and urea in solution, that is secreted by the sweat glands in the skin of mammals. ... Feces, faeces, or fæces (see spelling differences) is waste product from an animals digestive tract expelled through the anus (or cloaca) during defecation. ... This article or section is in need of attention from an expert on the subject. ... This article is about the term salt as referred to in chemistry. ... Annual mean sea surface temperature for the World Ocean. ...


Ordinarily, even a small rise in the serum sodium concentration above the normal range results in a strong sensation of thirst, an increase in free water intake, and correction of the abnormality. Therefore, hypernatremia most often occurs in people such as infants, those with impaired mental status, or the elderly, who may have an intact thirst mechanism but are unable to ask for or obtain water. William-Adolphe Bouguereaus Thirst (1886) Thirst is the basic need or instinct of humans or animals to drink. ... The human infant An infant or baby is an extremely young person. ... Look up Cognition in Wiktionary, the free dictionary. ...

Contents

Etiology

Common causes of hypernatremia include: Image File history File links Download high-resolution version (635x825, 60 KB) This flowchart is self made and is based on the information obtained from the The Washington Manual of Medical Therapeutics (29th Edition) I, the creator of this work, hereby grant the permission to copy, distribute and/or modify...

  • Inadequate intake of water, typically in elderly or otherwise disabled patients who are unable to take in water as their thirst dictates. This is the most common cause of hypernatremia.
  • Inappropriate excretion of water, often in the urine, which can be due to medications like diuretics or lithium or can be due to a medical condition called diabetes insipidus
  • Intake of a hypertonic fluid (a fluid with a higher concentration of solutes than the remainder of the body). This is relatively uncommon, though it can occur after a vigorous resuscitation where a patient receives a large volume of a concentrated sodium bicarbonate solution.
  • Mineral-corticoid excess due to a disease state such as Conn's or Cushing's Syndrome

A diuretic (colloquially called a water pill) is any drug or herb that elevates the rate of bodily urine excretion (diuresis). ... General Name, Symbol, Number lithium, Li, 3 Chemical series alkali metals Group, Period, Block 1, 2, s Appearance silvery white/grey Atomic mass 6. ... Diabetes insipidus (DI) is a disease characterized by excretion of large amounts of severely diluted urine, which cannot be reduced when fluid intake is reduced. ...

Symptoms

Clinical manifestations of hypernatremia can be subtle, consisting of lethargy, weakness, irritability, and edema. With more severe elevations of the sodium level, seizures and coma may occur. Fatigue is a feeling of excessive tiredness or lethargy, with a desire to rest, perhaps to sleep. ... Edema (American English) or oedema (British English), formerly known as dropsy or hydropsy, is swelling of any organ or tissue due to accumulation of excess lymph fluid, without an increase of the number of cells in the affected tissue. ... This article is about the medical term, epileptic seizure, as distinct from psychogenic non-epileptic seizure. ... Comatose redirects here. ...


Severe symptoms usually require an acute elevation in the plasma sodium concentration to above 158 mEq/L (normal is typically about 135-145 mEq/L). Values above 180 mEq/L are associated with a high mortality rate, particularly in adults. This may be due, in part, to the fact that such high levels of sodium rarely occur without severe coexisting medical conditions.


Treatment

The cornerstone of treatment is administration of free water to correct the relative water deficit. Water can be replaced orally or intravenously. However, overly rapid correction of hypernatremia is potentially very dangerous. The body (in particular the brain) adapts to the higher sodium concentration. Rapidly lowering the sodium concentration with free water, once this adaptation has occurred, causes water to flow into brain cells and causes them to swell. This can lead to cerebral edema, potentially resulting in seizures, permanent brain damage, or death. Therefore, significant hypernatremia should be treated carefully by a physician or other medical professional with experience in treatment of electrolyte imbalances. An intravenous drip in a hospital Intravenous therapy or IV therapy is the administration of liquid substances directly into a vein. ... In animals, the brain, or encephalon (Greek for in the head), is the control center of the central nervous system. ... Cerebral edema is swelling of the brain which can occur as the result of a head injury, cardiac arrest or from the lack of proper altitude acclimatization. ... Brain damage or brain injury is the destruction or degeneration of brain cells. ... The Doctor by Samuel Luke Fildes This article is about the term physician, one type of doctor; for other uses of the word doctor see Doctor. ... Electrolyte disturbance refers to an abnormal change in the levels of electrolytes in the body. ...


See also


  Results from FactBites:
 
Hypernatremia Information on Healthline (770 words)
Hypernatremia does not occur in diabetes insipidus if the patient is able to drink enough water to keep up with urinary loss, which may be as high as 10 liters per day.
Hypernatremia can also occur accidentally in the hospital when patients are infused with solutions containing sodium, such as sodium bicarbonate for the treatment of acidosis (acidic blood).
Hypernatremia is diagnosed by acquiring a blood sample, preparing plasma, and using a sodium-sensitive electrode for measuring the concentration of sodium ions.
Hypernatremia (918 words)
Hypernatremia is treated with infusions of a solution of water containing 0.9% sodium chloride (0.9 grams NaCl/100 ml water), which is the normal concentration of sodium chloride in the blood plasma.
In emergencies, such as when hypernatremia is causing neurological symptoms, infusions may be conducted with salt solutions containing 0.45% sodium chloride, which is half the normal physiologic level.
Hypernatremia occurs only in unusual circumstances that are not normally under a person's control.
  More results at FactBites »


 

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