Hypervitaminosis D
Classification & external resources

Cholecalciferol (shown above) and ergocalciferol are the two major forms of Vitamin D.
ICD-10	E67.3
ICD-9	278.4
DiseasesDB	13939

Hypervitaminosis D is a state of Vitamin D toxicity. Image File history File links Download high resolution version (3090x2631, 16 KB) Summary Chemical structure of cholecalciferol. ... Chemical structure of cholecalciferol Cholecalciferol is a form of Vitamin D, also called vitamin D3. ... Ergocalciferol (Deltalin®, Eli Lilly and Company) is a form of Vitamin D, also called vitamin D2. ... Vitamin D is a fat soluble vitamin that contributes to the maintenance of normal levels of calcium and phosphorus in the bloodstream. ... The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) is a coding of diseases and signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or diseases, as classified by the World Health Organization (WHO). ... // E00-E35 - Endocrine diseases (E00-E07) Disorders of thyroid gland (E00) Congenital iodine-deficiency syndrome (E01) Iodine-deficiency-related thyroid disorders and allied conditions (E02) Subclinical iodine-deficiency hypothyroidism (E03) Other hypothyroidism (E030) Congenital hypothyroidism with diffuse goitre (E031) Congenital hypothyroidism without goitre (E032) Hypothyroidism due to medicaments and other... The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ... The Disease Bold textDatabase is a free website that provides information about the relationships between medical conditions, symptoms, and medications. ... Vitamin D is a fat soluble vitamin that contributes to the maintenance of normal levels of calcium and phosphorus in the bloodstream. ...

In terms of the likelihood of poisoning, Vitamin D seems to be one of the least poisonous substances known. Overdose occurs at more than 100 times the recommended daily allowance (more or less a bottle of vitamin D tablets per day), for several months. Acute one-time overdose requires over 50mg (ten thousand times the RDA). Foods contain low levels, and have not been known to cause overdose. Overdose has occurred due to industrial accidents, for example when incorrectly formulated pills were sold or missing industrial concentrate cans misused as cans of milk. Reference Daily Intake (RDI) is the daily dietary intake level of a nutrient considered sufficient to meet the requirements of nearly all (97–98%) healthy individuals in each life-stage and gender group. ... A glass of cows milk. ...

Symptoms and presentation

Symptoms of vitamin D poisoning include:

• Dehydration
• Vomiting
• Decreased appetite (anorexia)
• Irritability
• Constipation
• Fatigue

An excess of vitamin D causes abnormally high blood concentrations of calcium (hypercalcemia) which can eventually cause severe damage to the bones, soft tissues, and kidneys. It can also damage the kidney and produce kidney stones. Ongoing research indicates antagonism with oil soluble menatetrenone, MK-4, an internally transported natural form of vitamin K₂, which is associated with bone formation and calcium retention in the bones. Dehydration (hypohydration) is the removal of water (hydro in ancient Greek) from an object. ... Vomiting (also throwing up or emesis) is the forceful expulsion of the contents of ones stomach through the mouth and sometimes the nose. ... The appetite is the desire to eat food, felt as hunger. ... Anorexia (deriving from the Greek α(ν)- (a(n)-, a prefix that denotes absence) + όρεξη (orexe) = appetite) is the decreased sensation of appetite. ... Irritability is an excessive response to stimuli. ... Constipation or irregularity, is a condition of the digestive system where a person (or animal) experiences hard feces that are difficult to egest; it may be extremely painful, and in severe cases (fecal impaction) lead to symptoms of bowel obstruction. ... “Fatigue (physical)” redirects here. ... Human blood smear: a - erythrocytes; b - neutrophil; c - eosinophil; d - lymphocyte. ... General Name, Symbol, Number calcium, Ca, 20 Chemical series alkaline earth metals Group, Period, Block 2, 4, s Appearance silvery white Standard atomic weight 40. ... Hypercalcaemia is an elevated calcium level in the blood. ... A miserable stubborn cantankerous old mans, whos actually quite good humoured & an enjoyable compadre to play online alongside if you catch him on a good day. ... In medicine, the term soft tissue refers to tissues that connect, support, or surround other structures and organs of the body. ... Kidneys viewed from behind with spine removed The kidneys are bean-shaped excretory organs in vertebrates. ... Kidney stones are solid accretions (crystals) of dissolved minerals in urine found inside the kidneys or ureters. ... Menatetrenone (INN) is a menaquinone compound used as a hemostatic agent and as adjunctive therapy for the pain of osteoporosis. ... Vitamin K1 (phylloquinone). ...

Note: Hypervitaminosis D symptoms appear several months after excessive doses of vitamin D are administered. In almost every case, a low calcium diet combined with corticosteroid drugs will allow for a full recovery within a month.

Comparative safety statistics

Deaths by vitamin poisoning appear to be quite rare in the US, typically none in a given year. However before 1998, several deaths per year were typically associated with pharmaceutical iron-containing supplements, especially brightly-colored, sugar-coated, high-potency iron supplements, and most deaths were children[1]. Unit packaging restrictions on supplements with more than 30 mg iron have since reduced deaths to 0 or 1 per year[2]. These statistics compare with 59 deaths due to aspirin poisoning in 2003, 147 deaths associated with acetaminophen-containing products in 2003, and an average of 54 deaths per year due to lightning for 1990-2003. This article or section does not adequately cite its references or sources. ...

See also

• Vitamin poisoning

Vitamin poisoning, or hypervitaminosis, refers to a condition of high storage levels of vitamins, which can lead to toxic symptoms. ...

External links

• Hypervitaminosis D Medical Information