| Serum Inorganic Phosphorus (2362 words) |
 | A characteristic of severe hypophosphatemia is skeletal muscle damage with an elevation of the serum creatine phosphokinase and aldolase levels, and in some cases rhabdomyolysis. |
| The three primary mechanisms leading to hypophosphatemia are: (1) transcellular shift of phosphorus (from extracellular volume to either soft tissues or bones); (2) poor dietary intake, especially when associated with impaired GI absorption or diarrhea; and (3) increased phosphate excretion resulting from renal and nonrenal causes. |
| Hypophosphatemia may be seen in 50% of patients hospitalized with chronic alcoholism. |
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