| Interactive Fly, Drosophila (3138 words) |
 | The effects of ectopic expression of imd on the transcription of antibacterial peptides and on the generation of TUNEL-reactive cells are blocked by coexpression of the baculovirus antiapoptotic protein P35. |
| The presence in IMD of a death domain with similarity to that of the adaptor protein RIP suggests that the IMD protein may be part of a receptor-adaptor complex. |
| In addition to imd, four death domain-containing proteins have been described in Drosophila: (1) the serine/threonine kinase Pelle, a homolog of the mammalian kinases IRAKs, which are associated with the IL-1 and the Toll-like receptors; (2) the adaptor protein Tube; (3) DmFADD, the Drosophila homolog of FADD. |
Feeds |
Contact