IS/1 [1] was the world's first relational database system, implemented at the IBM United Kingdom Scientific Centre in Peterlee in the years 1970-1972. It had limited facilities but implemented a true relational model. It was the precursor to PRTV. Jump to: navigation, search PRTV (Peterlee Relational Test Vehicle [1,2]) was the worlds first relational database management system that could handle significant data volumes -- it was really a relational query system as it had very powerful query facilities, but very limited update facility and no simultaneous multiuser facility. ...
[1] Notley, M, "Peterlee IS/1 System", UKSC Report 18, 1972
IS1 was one of the first bacterial insertion sequences to be isolated and characterized (139, 199).
IS1 is a component of several compound transposons such as Tn9 (301) and Tn1681 (447), where it is present in direct or inverted orientation flanking a chloramphenicol acetyltrans-ferase and heat-stable toxin gene, respectively.
Although the relative activities of mutants at these positions in IS1 parallel those of similar mutants in the Flp recombinase (436), this triad is not fully conserved in IS1Sa: while the R residue is conserved, the upstream H occurs one residue further upstream and the conserved Y is replaced by an F residue.
IS1 also carries two imperfect inverted terminal repeats about 23 bp long, shown in bold type, and is bracketed by a 9- bp duplication of the target sequence, shown in italics (22, 41).
Occurrence of IS1 and IS10 elements in the serovar Typhimurium chromosome.
IS1 is involved in deletion formation in the gal region of E.
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