The International Standard Music Number or ISMN is a ten-character alphanumeric identifier for printed music. It consists of four blocks: the prefix M to distinguish it from ISBNs, a block to identify the publisher, another to identify the item and one final check digit.
A publication may be assigned both an ISBN and an ISMN. Unlike the ISBN, the ISMN does not segregate publishers by country.
To calculate the check digit, each digit of the ISMN is multiplied by a weight, alternating 3 and 1 left to right. The letter M counts as 3. These weighted digits are added together. The check digit is the integer between 0 and 9 which makes the sum a multiple of 10.
For instance, for the item with ISMN beginning M-060-11561:
ISMN is a white, crystalline, odorless compound which is stable in air and in solution, has a melting point of about 90°C, and an optical rotation of +144° (2% in water, 20°C).
The principal pharmacological action of ISMN and all organic nitrates in general is relaxation of vascular smooth muscle, producing dilatation of peripheral arteries and veins, especially the latter.
The disposition of ISMN in patients with various degrees of renal insufficiency, liver cirrhosis, or cardiac dysfunction was evaluated and found to be similar to that observed in healthy subjects.
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