Indazole is a heterocyclic aromaticorganic compound. IUPAC nomenclature is a systematic way of naming organic chemical compounds. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... The molecular mass of a substance (less accurately called molecular weight and abbreviated as MW) is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... The melting point of a solid is the temperature at which it changes state from solid to liquid. ... The boiling point of a substance is the temperature at which it can change state from a liquid to a gas throughout the bulk of the liquid. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... The simplified molecular input line entry specification or SMILES is a specification for unambiguously describing the structure of chemical molecules using short ASCII alpha-numeric strings. ... Heterocyclic compounds are substances which contain a ring structure as found in benzene and the aromatic compounds, or aromatic hydrocarbons, but in which other atoms than carbon, such as sulfur, oxygen or nitrogen are found as part of the ring. ... In chemistry, an aromatic molecule is one in which electrons are free to cycle around circular arrangements of atoms, which are alternately singly and doubly bonded to one another. ... An organic compound refers to any member of a large class of chemical compounds whose molecules contain carbon, with exception of carbides, carbonates and carbon oxides. ...
The parent substance N/N N indazole, C7H6N2, was obtained by E. Fischer (Ann.
Nitrous acid converts it into nitrosoindazole; whilst on heating with the alkyl iodides it is converted into alkyl indazoles.
A series of compounds isomeric with these alkyl derivatives is known, and can be considered as derived from the ring system / NH N. N/NCH7 be prepared by the reduction of the nitroso-ortho-alkylaminoacetophenones with zinc dust and water or acetic acid.
Indazole compounds and compositions thereof as JNK inhibitors and for the treatment of diseases associated therewith
Indazole compounds that modulate and/or inhibit the activity of certain protein kinases are described.
The invention is directed to novel indazole peptidomimetic compounds which are useful as thrombin receptor antagonists for the treatment of diseases associated with thrombosis, restenosis, hypertension, heart failure, arrhythmia, inflamm...
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